Evidence map›Paper›PMID 32252671›Full record

SynthesisBMC cancer2020

Dietary factors and risk of mortality among patients with esophageal cancer: a systematic review.

Li-Ping Sun, Lu-Bin Yan, Zhen-Zhen Liu, Wen-Jing Zhao, Cai-Xia Zhang, Yu-Min Chen, Xiang Qian Lao, Xudong Liu

Abstract readSystematic Review
In one paragraph

Synthesis in BMC cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  3. Vitamins andFrontiers in nutrition · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Li-Ping SunDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Lu-Bin YanDepartment of Pediatric Surgery, the Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Zhen-Zhen LiuDepartment of Radiology, the Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Wen-Jing ZhaoDepartment of Public Health, Faculty of Medicine, Hokkaido University, Sapporo, Japan.
Cai-Xia ZhangDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Yu-Min ChenDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Xiang Qian LaoJC School of Public Health and Primary care, the Chinese University of Hong Kong, Hong Kong, China.
Xudong LiuDepartment of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, China. liuxudong@mail.sysu.edu.cn.

Funding

Natural Science Foundation of Guangdong Province 2019A15150115990
6 · The paper itself

Abstract

backgroundThe effects of dietary factors on prognosis of esophageal cancer remain unclear. This systematic review and meta-analysis aimed to assess the association between dietary intake and the risk of mortality among patients with esophageal cancer.

methodsSix electronic databases (PubMed, Web of Science, OVID, ProQuest, CNKI and Wanfang) were searched for studies published up to Oct. 2019 that examined the association between dietary intake and all-cause mortality, esophageal cancer-specific mortality and esophageal cancer recurrence. The pooled hazard ratio (HR) with 95% confidence interval (CI) were derived by comparing the highest with the lowest categories of each dietary item and by using random effect models.

resultsA total of 15 cohort studies were included in this study and all reported pre-diagnosis dietary exposure; two focused on dietary folate, 12 on alcohol consumption and three on other dietary components (sugary beverages, phytochemicals and preserved vegetables). When comparing the highest with the lowest categories, dietary folate intake was associated with a reduced risk of esophageal cancer-specific mortality in patients with esophageal squamous cell carcinoma (HR: 0.41, 95% CI: 0.25-0.69), with low heterogeneity (I

conclusionsThis review with pre-diagnostic dietary exposure showed that dietary folate intake was associated with a reduced risk of mortality of esophageal squamous cell carcinoma, whereas alcohol consumption was associated with an increased risk. More studies are needed to investigate effect of dietary factors, especially post-diagnosis dietary consumption, on esophageal cancer prognosis.

Indexed as

Nutritional StatusAlcohol DrinkingBeveragesDietEsophageal NeoplasmsEsophageal Squamous Cell CarcinomaFolic AcidHumansNeoplasm Recurrence, LocalPrognosisProportional Hazards ModelsRisk FactorsSurvival RateVitamin B ComplexFolic AcidVitamin B ComplexDietary intakeEsophageal CancerMeta-analysisMortalitySystematic review

Identifiers

PMID32252671
PMCPMC7137267

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.