Evidence map›Paper›PMID 32252637›Full record

Observational studyBMC cardiovascular disorders2020

Trends and predictors of early ablation for Atrial Fibrillation in a Nationwide population under age 65: a retrospective observational study.

Robert N D'Angelo, Rahul Khanna, Robert W Yeh, Laura Goldstein, Iftekhar Kalsekar, Stephen Marcello, Patricia Tung, Peter J Zimetbaum

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Robert N D'AngeloRichard A. and Susan F. Smith Center for Outcomes Research, Division of Cardiology, Beth Israel Deaconess Medical Center, 185 Pilgrim Road, Boston, MA, 02215, USA.
Rahul KhannaMedical Device Epidemiology and Real World Data Science, Johnson and Johnson, New Brunswick, NJ, USA.
Robert W YehRichard A. and Susan F. Smith Center for Outcomes Research, Division of Cardiology, Beth Israel Deaconess Medical Center, 185 Pilgrim Road, Boston, MA, 02215, USA.
Laura GoldsteinFranchise Health Economics and Market Access, Johnson and Johnson, New Brunswick, NJ, USA.
Iftekhar KalsekarMedical Device Epidemiology and Real World Data Science, Johnson and Johnson, New Brunswick, NJ, USA.
Stephen MarcelloMedical Safety, Johnson and Johnson, New Brunswick, NJ, USA.
Patricia TungRichard A. and Susan F. Smith Center for Outcomes Research, Division of Cardiology, Beth Israel Deaconess Medical Center, 185 Pilgrim Road, Boston, MA, 02215, USA.
Peter J ZimetbaumRichard A. and Susan F. Smith Center for Outcomes Research, Division of Cardiology, Beth Israel Deaconess Medical Center, 185 Pilgrim Road, Boston, MA, 02215, USA. pzimetba@bidmc.harvard.edu.
Johnson & Johnson (United States) · USBeth Israel Deaconess Medical Center · USDeaconess Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCatheter ablation (CA) has emerged as an effective treatment for symptomatic atrial fibrillation (AF). However practice patterns and patient factors associated with referral for CA within the first 12 months after diagnosis are poorly characterized. This study examined overall procedural trends and factors predictive of catheter ablation for newly-diagnosed atrial fibrillation in a young, commercially-insured population.

methodsA large nationally-representative sample of patients age 20 to 64 from years 2010 to 2016 was studied using the IBM MarketScan® Commercial Database. Patients were included with a new diagnosis of AF in the inpatient or outpatient setting with continuous enrollment for at least 1 year pre and post index visit. Patients were excluded if they had prior history of AF or had filled an anti-arrhythmic drug (AAD) in the pre-index period.

resultsEarly CA increased from 5.0% in 2010 to 10.5% in 2016. Patients were less likely to undergo CA if they were located in the Northeast (OR: 0.80, CI: 0.73-0.88) or North Central (OR: 0.91, CI: 0.83-0.99) regions (compared with the West), had higher CHA

conclusionsCA within 12 months for new-diagnosed AF increased significantly from 2010 to 2016, with most patients still trialed on an AAD prior to CA. Patients are less likely to be referred for early CA if they are located in the Northeast and North Central regions, have more comorbidities, or higher CHA

Indexed as

AdultAge FactorsAtrial FibrillationCatheter AblationComorbidityFemaleHealthcare DisparitiesHumansMaleMiddle AgedPractice Patterns, Physicians'Residence CharacteristicsRetrospective StudiesRisk FactorsTime FactorsTime-to-TreatmentAtrial fibrillationCatheter ablationRhythm control

Identifiers

PMID32252637
PMCPMC7137521
OpenAlexW3015008808

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.