Evidence map›Paper›PMID 32252601›Full record

ArticleStroke2020

Atrial Fibrillation Risk and Discrimination of Cardioembolic From Noncardioembolic Stroke.

Shaan Khurshid, Ludovic Trinquart, Lu-Chen Weng, Olivia L Hulme, Wyliena Guan, Darae Ko, Kristin Schwab, Natalia S Rost, Mostafa A Al-Alusi, Emelia J Benjamin and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Stroke, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. [Prognostic analysis of anticoagulation therapy in elderly patients with cardioembolic stroke].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Shaan KhurshidFrom the Division of Cardiology (S.K.), Massachusetts General Hospital, Boston.
Ludovic TrinquartDepartment of Biostatistics (L.T.), Boston University School of Public Health, MA.
Lu-Chen WengCardiovascular Research Center, Massachusetts General Hospital, Boston (S.K., L.W., W.G., P.T.E., S.A.L.).
Olivia L HulmeDepartment of Medicine, Brigham and Women's Hospital, Boston, MA (O.L.H.).
Wyliena GuanCardiovascular Research Center, Massachusetts General Hospital, Boston (S.K., L.W., W.G., P.T.E., S.A.L.).
Darae KoBoston University and National Heart, Lung, and Blood Institute's Framingham Heart Study, MA (L.T., D.K., E.J.B.).
Kristin SchwabDepartment of Neurology (K.S., N.S.R., C.D.A.), Massachusetts General Hospital, Boston.
Natalia S RostDepartment of Neurology (K.S., N.S.R., C.D.A.), Massachusetts General Hospital, Boston.
Mostafa A Al-AlusiDepartment of Medicine (M.A.A.-A.), Massachusetts General Hospital, Boston.
Emelia J BenjaminDepartment of Epidemiology (E.J.B.), Boston University School of Public Health, MA.
Patrick T EllinorCardiac Arrhythmia Service, Division of Cardiology, (P.T.E., S.A.L.), Massachusetts General Hospital, Boston.
Christopher D Anderson *Center for Genomic Medicine (C.D.A.), Massachusetts General Hospital, Boston.
Steven A Lubitz *Cardiac Arrhythmia Service, Division of Cardiology, (P.T.E., S.A.L.), Massachusetts General Hospital, Boston.
Massachusetts General Hospital · USBoston University · USBrigham and Women's Hospital · USNational Heart Lung and Blood Institute · US

Funding

IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVALR01HL092577 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2009 to 2025
$20.6M
ConProject-006U54HL120163 · NHLBI · AMERICAN HEART ASSOCIATION · PI BHATNAGAR, ARUNI, ROBERTSON, ROSE MARIE · 2018 to 2022
$18.8M
MULTIDISCIPLINARY RESEARCH TRAINING IN CARDIOLOGYT32HL007208 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI Patrick Thomas Ellinor, David E Sosnovik · 1985 to 2026
$16.1M
Sequencing Annotation and Functional Analysis in Risk of Intracerebral HemorrhageR01NS103924 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI ANDERSON, CHRISTOPHER DAVID · 2018 to 2022
$3.4M
Genomics of Cardiac ArrhythmiasR01HL139731 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ELLINOR, PATRICK THOMAS · 2018 to 2022
$3.3M
MRI-GENetics Interface Exploration_MRI-GENIE_StudyR01NS086905 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI ROST, NATALIA S · 2015 to 2019
$3.3M
AFGen Consortium: Atrial Fibrillation Genomics to Functional AnalysesR01HL128914 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2015 to 2018
$3.1M
Statins augment small vessel function and improve stroke outcomesR01NS082285 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI ROST, NATALIA S · 2013 to 2017
$2.6M
FHS-NEXT - Framingham Novel EXam using TechnologyR01HL141434 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI BENJAMIN, EMELIA J., MCMANUS, DAVID D. · 2019 to 2022
$2.5M
Mentoring in Arrhythmia ResearchK24HL105780 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI ELLINOR, PATRICK THOMAS · 2011 to 2020
$1.2M
Genetic variation in white matter hyperintensity and risk of ischemic strokeK23NS064052 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI ROST, NATALIA S · 2009 to 2013
$915k
American Heart Association-American Stroke Association 18SFRN34110082NHLBI NIH HHS K24 HL105780NHLBI NIH HHS R01 HL092577NHLBI NIH HHS R01 HL128914NHLBI NIH HHS R01 HL139731NHLBI NIH HHS R01 HL141434NHLBI NIH HHS T32 HL007208NHLBI NIH HHS U54 HL120163NINDS NIH HHS K23 NS064052NINDS NIH HHS R01 NS082285NINDS NIH HHS R01 NS086905NINDS NIH HHS R01 NS103924
6 · The paper itself

Abstract

Background and Purpose- Classification of stroke as cardioembolic in etiology can be challenging, particularly since the predominant cause, atrial fibrillation (AF), may not be present at the time of stroke. Efficient tools that discriminate cardioembolic from noncardioembolic strokes may improve care as anticoagulation is frequently indicated after cardioembolism. We sought to assess and quantify the discriminative power of AF risk as a classifier for cardioembolism in a real-world population of patients with acute ischemic stroke. Methods- We performed a cross-sectional analysis of a multi-institutional sample of patients with acute ischemic stroke. We systematically adjudicated stroke subtype and examined associations between AF risk using CHA

Indexed as

AdultAgedAged, 80 and overAnticoagulantsAtrial FibrillationBrain IschemiaCross-Sectional StudiesFemaleHumansMaleMiddle AgedRisk AssessmentRisk FactorsStrokeAnticoagulantsatrial fibrillationhearthumansodds ratiostroke

Identifiers

PMID32252601
PMCPMC7188588
OpenAlexW3014382841

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.