Evidence map›Paper›PMID 32252524›Full record

ArticleAnalytical chemistry2020

Virus Bioresistor (VBR) for Detection of Bladder Cancer Marker DJ-1 in Urine at 10 pM in One Minute.

Apurva Bhasin, Emily C Sanders, Joshua M Ziegler, Jeffrey S Briggs, Nicholas P Drago, Aisha M Attar, Alicia M Santos, Marie Y True, Alana F Ogata, Debora V Yoon and 5 more

Erratum issuedOpen access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 30 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Apurva BhasinDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.
Emily C SandersDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.ORCID 0000-0003-1043-5772
Joshua M ZieglerDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.
Jeffrey S BriggsPhageTech Inc., 5 Mason, Suite 170, Irvine, California 92618, United States.
Nicholas P DragoDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.
Aisha M AttarDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.ORCID 0000-0002-0200-2945
Alicia M SantosDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.
Marie Y TruePhageTech Inc., 5 Mason, Suite 170, Irvine, California 92618, United States.
Alana F OgataDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.
Debora V YoonDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.
Sudipta MajumdarDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.
Andrew J WheatDepartment of Molecular Biology & Biochemistry, University of California, Irvine, Irvine, California 92697, United States.
Shae V PattersonDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.
Gregory A WeissDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.ORCID 0000-0003-0296-9846
Reginald M PennerDepartment of Chemistry, University of California, Irvine, Irvine, California 92697, United States.ORCID 0000-0003-2831-3028
University of California, Irvine · US

Funding

Monitoring Recurrent Bladder Cancer with Electro-Phage BiosensorsR33CA206955 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI WEISS, GREGORY A. · 2016 to 2018
$932k
NCI NIH HHS R33 CA206955
6 · The paper itself

Abstract

DJ-1, a 20.7 kDa protein, is overexpressed in people who have bladder cancer (BC). Its elevated concentration in urine allows it to serve as a marker for BC. However, no biosensor for the detection of DJ-1 has been demonstrated. Here, we describe a virus bioresistor (

Indexed as

Biosensing TechniquesBacteriophage M13Biomarkers, TumorHumansProtein Deglycase DJ-1Time FactorsUrinary Bladder NeoplasmsBiomarkers, TumorPARK7 protein, humanProtein Deglycase DJ-1

Identifiers

PMID32252524
PMCPMC7266010
OpenAlexW3014173799

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.