Evidence map›Paper›PMID 32252467›Full record

ReviewBiomolecules2020

Biotechnological Interventions for Ginsenosides Production.

Saikat Gantait, Monisha Mitra, Jen-Tsung Chen

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Active Compounds ofPharmaceuticals (Basel, Switzerland) · 2023
    Review
  7. Article
  8. Review
  9. Promoting Photosynthetic Production of Dammarenediol-II inInternational journal of molecular sciences · 2023
    Article
  10. Review
  11. Article
  12. Ginsenosides inActa pharmaceutica Sinica. B · 2021
    Review
  13. PlantFrontiers in plant science · 2021
    Review
  14. Article
  15. Advances in Ginsenosides.Biomolecules · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Saikat GantaitCrop Research Unit (Genetics and Plant Breeding), Bidhan Chandra Krishi Viswavidyalaya, Mohanpur, Nadia, West Bengal 741252, India.
Monisha MitraDepartment of Agricultural Biotechnology, Faculty of Agriculture, Bidhan Chandra Krishi Viswavidyalaya, Mohanpur, Nadia, West Bengal 741252, India.
Jen-Tsung ChenDepartment of Life Sciences, National University of Kaohsiung, Kaohsiung 811, Taiwan.
Bidhan Chandra Krishi Viswavidyalaya · INNational University of Kaohsiung · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ginsenosides are secondary metabolites that belong to the triterpenoid or saponin group. These occupy a unique place in the pharmaceutical sector, associated with the manufacturing of medicines and dietary supplements. These valuable secondary metabolites are predominantly used for the treatment of nervous and cardiac ailments. The conventional approaches for ginsenoside extraction are time-consuming and not feasible, and thus it has paved the way for the development of various biotechnological approaches, which would ameliorate the production and extraction process. This review delineates the biotechnological tools, such as conventional tissue culture, cell suspension culture, protoplast culture, polyploidy, in vitro mutagenesis, hairy root culture, that have been largely implemented for the enhanced production of ginsenosides. The use of bioreactors to scale up ginsenoside yield is also presented. The main aim of this review is to address the unexplored aspects and limitations of these biotechnological tools, so that a platform for the utilization of novel approaches can be established to further increase the production of ginsenosides in the near future.

Indexed as

AgrobacteriumBiotechnologyGinsenosidesTransformation, GeneticGinsenosidesbioreactorcell suspensionhairy rootpolyploidyprotoplast

Identifiers

PMID32252467
PMCPMC7226488
OpenAlexW3014516121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.