Evidence map›Paper›PMID 32252424›Full record

ArticleJournal of clinical medicine2020

A Pilot Study Evaluating the Effects of 670 nm Photobiomodulation in Healthy Ageing and Age-Related Macular Degeneration.

Manjot K Grewal, Chrishne Sivapathasuntharam, Shruti Chandra, Sarega Gurudas, Victor Chong, Alan Bird, Glen Jeffery, Sobha Sivaprasad

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Manjot K GrewalInstitute of Ophthalmology, University College London, London EC1V 9EL, UK.
Chrishne SivapathasuntharamInstitute of Ophthalmology, University College London, London EC1V 9EL, UK.
Shruti ChandraInstitute of Ophthalmology, University College London, London EC1V 9EL, UK.
Sarega GurudasInstitute of Ophthalmology, University College London, London EC1V 9EL, UK.
Victor ChongEretina Ltd. 8, Spruce Dene, Hazlemere, Bucks HP15 7QF, UK.
Alan BirdInstitute of Ophthalmology, University College London, London EC1V 9EL, UK.
Glen JefferyInstitute of Ophthalmology, University College London, London EC1V 9EL, UK.
Sobha SivaprasadInstitute of Ophthalmology, University College London, London EC1V 9EL, UK.ORCID 0000-0001-8952-0659

Funding

Fight for Sight UK 1409Moorfields Eye Charity 670
6 · The paper itself

Abstract

Limited evidence suggests that the application of 670 nm of red light alters the course of aged decline. A previous report on 18 patients showed regression of drusen and improvement in visual functions in patients with intermediate age-related macular degeneration (AMD) by 12 months. We evaluated the functional and structural effects of applying 670 nm light to 31 patients with intermediate AMD and 11 people aged 55 years or above with normal retina. The study eyes were treated daily in the morning with a 670 nm hand-held light source housed in a torch-like tube that emitted energy equivalent to 40 mW/cm

Indexed as

670 nmage-related macular degenerationdark adaptationoptical coherence tomographyphotobiomodulationreticular pseudodrusenscotopic thresholdssubretinal drusenoid deposits

Identifiers

PMID32252424
PMCPMC7231137

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.