Evidence map›Paper›PMID 32252356›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Deep Functional Profiling Facilitates the Evaluation of the Antibacterial Potential of the Antibiotic Amicoumacin.

Stanislav S Terekhov, Anton S Nazarov, Yuliana A Mokrushina, Margarita N Baranova, Nadezhda A Potapova, Maja V Malakhova, Elena N Ilina, Ivan V Smirnov, Alexander G Gabibov

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Amicoumacins produced by the native citrus microbiome isolateApplied and environmental microbiology · 2025
    Article
  3. Review
  4. Modern Trends in Natural Antibiotic Discovery.Life (Basel, Switzerland) · 2023
    Review
  5. Deep Functional Profiling of Wild Animal Microbiomes Reveals ProbioticInternational journal of molecular sciences · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Liquid drop of DNA libraries reveals total genome information.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  10. Selective Eradication ofAntibiotics (Basel, Switzerland) · 2020
    Article
  11. Article
  12. Mechanism of the Potential Therapeutic CandidateFrontiers in microbiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stanislav S TerekhovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow 117997, Russia.ORCID 0000-0003-2220-0452
Anton S NazarovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow 117997, Russia.ORCID 0000-0003-4864-3462
Yuliana A MokrushinaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow 117997, Russia.ORCID 0000-0002-4669-9545
Margarita N BaranovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow 117997, Russia.
Nadezhda A PotapovaInstitute for Information Transmission Problems (Kharkevich Institute) of the Russian Academy of Sciences, Moscow 127051, Russia.
Maja V MalakhovaFederal Research and Clinical Centre of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow 119435, Russia.
Elena N IlinaFederal Research and Clinical Centre of Physical-Chemical Medicine of Federal Medical Biological Agency, Moscow 119435, Russia.
Ivan V SmirnovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow 117997, Russia.
Alexander G GabibovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry of the Russian Academy of Sciences, Moscow 117997, Russia.

Funding

Russian Science Foundation 19-14-00331Российский Фонд Фундаментальных Исследований (РФФИ) 18-29-08054Российский Фонд Фундаментальных Исследований (РФФИ) 19-34-70021
6 · The paper itself

Abstract

The global spread of antibiotic resistance is forcing the scientific community to find new molecular strategies to counteract it. Deep functional profiling of microbiomes provides an alternative source for the discovery of novel antibiotic producers and probiotics. Recently, we implemented this ultrahigh-throughput screening approach for the isolation of

Indexed as

amicoumacinamide stability toward hydrolysisantibiotic activity spectrumdeep functional profilingmulti-omicssingle-cellultrahigh-throughput screening

Identifiers

PMID32252356
PMCPMC7235827

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.