Evidence map›Paper›PMID 32252345›Full record

ArticleInternational journal of molecular sciences2020

The Aquaporin-3-Inhibiting Potential of Polyoxotungstates.

Catarina Pimpão, Inês V da Silva, Andreia F Mósca, Jacinta O Pinho, Maria Manuela Gaspar, Nadiia I Gumerova, Annette Rompel, Manuel Aureliano, Graça Soveral

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 57 citations in OpenAlex.

  1. Review
  2. Article
  3. Aquaporins: a novel perspective in the treatment of lung diseases.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Polyoxometalates Impact as Anticancer Agents.International journal of molecular sciences · 2023
    Review
  13. Aquaporin-mediated dysregulation of cell migration in disease states.Cellular and molecular life sciences : CMLS · 2023
    Review
  14. Article
  15. Article
  16. Clinical value and molecular mechanism of AQGPs in different tumors.Medical oncology (Northwood, London, England) · 2022
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Catarina PimpãoResearch Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisbon, Portugal.ORCID 0000-0002-2356-1105
Inês V da SilvaResearch Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisbon, Portugal.ORCID 0000-0002-2916-4848
Andreia F MóscaResearch Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisbon, Portugal.
Jacinta O PinhoResearch Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisbon, Portugal.ORCID 0000-0001-7725-4701
Maria Manuela GasparResearch Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisbon, Portugal.ORCID 0000-0001-6814-7226
Nadiia I GumerovaUniversität Wien, Fakultät für Chemie, Institut für Biophysikalische Chemie, 1090 Vienna, Austria.ORCID 0000-0003-4375-0103
Annette RompelUniversität Wien, Fakultät für Chemie, Institut für Biophysikalische Chemie, 1090 Vienna, Austria.ORCID 0000-0002-5919-0553
Manuel AurelianoFaculdade de Ciências e Tecnologia (FCT), CCMar, Universidade do Algarve, 8005-139 Faro, Portugal.ORCID 0000-0003-4858-3201
Graça SoveralResearch Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, 1649-003 Lisbon, Portugal.ORCID 0000-0001-8487-110X
University of Lisbon · PTUniversity of Vienna · ATUniversity of Algarve · PT

Funding

Austrian Science Fund FWF M 2203Austrian Science Fund FWF P 27534
6 · The paper itself

Abstract

Polyoxometalates (POMs) are of increasing interest due to their proven anticancer activities. Aquaporins (AQPs) were found to be overexpressed in tumors bringing particular attention to their inhibitors as anticancer drugs. Herein, we report for the first time the ability of polyoxotungstates (POTs), such as of Wells-Dawson P

Indexed as

AnimalsAquaporin 3Cell Line, TumorCell Membrane PermeabilityCell MovementDose-Response Relationship, DrugGlycerolHumansMelanomaMolecular StructurePolyoxometalatesTungsten CompoundsWaterAquaporin 3Glycerolpolyoxometalate IPolyoxometalatesTungsten CompoundsWateraquaglyceroporinaquaporincancerglycerolinhibitorsmelanomapolyoxotungstates

Identifiers

PMID32252345
PMCPMC7177757
OpenAlexW3014808464

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.