Evidence map›Paper›PMID 32252341›Full record

ArticleCells2020

Failure to Down-Regulate

Cho-Ming Chao, Gianni Carraro, Zvonimir A Rako, Johannes Kolck, Jamschid Sedighi, Volker Zimmermann, Alena Moiseenko, Jochen Wilhelm, Brittany M Young, Lei Chong and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
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  6. American journal of respiratory and critical care medicine · 2020
    Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 8 institutions in 4 countries.

Cho-Ming ChaoKey laboratory of Interventional Pulmonology of Zhejiang Province, Department of Pulmonary and Critical Care Medicine, First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang, China.
Gianni CarraroCedars-Sinai Medical Center, Lung and Regenerative Medicine Institutes, Department of Medicine, Los Angeles, CA, 90027, USA.
Zvonimir A RakoCardio-Pulmonary Institute and Institute for Lung Health, Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research, Justus-Liebig-University Giessen, 35392 Giessen, Germany.
Johannes KolckCardio-Pulmonary Institute and Institute for Lung Health, Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research, Justus-Liebig-University Giessen, 35392 Giessen, Germany.
Jamschid SedighiCardio-Pulmonary Institute and Institute for Lung Health, Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research, Justus-Liebig-University Giessen, 35392 Giessen, Germany.
Volker ZimmermannCardio-Pulmonary Institute and Institute for Lung Health, Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research, Justus-Liebig-University Giessen, 35392 Giessen, Germany.
Alena MoiseenkoCardio-Pulmonary Institute and Institute for Lung Health, Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research, Justus-Liebig-University Giessen, 35392 Giessen, Germany.
Jochen WilhelmCardio-Pulmonary Institute and Institute for Lung Health, Universities of Giessen and Marburg Lung Center, Member of the German Center for Lung Research, Justus-Liebig-University Giessen, 35392 Giessen, Germany.ORCID 0000-0001-5544-9647
Brittany M YoungDepartment of Neurology, University of California, Los Angeles, CA 90095, USA.
Lei ChongInstitute of Pediatrics, Discipline of Pediatric Respiratory Medicine, Second Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang, China.
Jin WuCollege of Life and Environmental Sciences, Wenzhou University, Wenzhou 325027, Zhejiang, China.
Adriana ContrerasLung Cancer Epigenetics, Member of the German Center of Lung Research (Deutsches Zentrum für Lungenforschung, DZL), Max-Planck-Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.
Parviz MinooDepartment of Pediatrics, Division of Newborn Medicine, University of Southern California, Children's Hospital Los Angeles, Los Angeles, CA 90027, USA.
Guillermo BarretoLung Cancer Epigenetics, Member of the German Center of Lung Research (Deutsches Zentrum für Lungenforschung, DZL), Max-Planck-Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany.ORCID 0000-0002-7777-4712
David WarburtonDevelopmental Biology and Regenerative Medicine Program, Saban Research Institute of Children's Hospital Los Angeles and University of Southern California, Los Angeles, CA 90027, USA.
Saverio BellusciKey laboratory of Interventional Pulmonology of Zhejiang Province, Department of Pulmonary and Critical Care Medicine, First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325027, Zhejiang, China.ORCID 0000-0001-5987-4579
Justus-Liebig-Universität Gießen · DEUniversity of Southern California · USCedars-Sinai Medical Center · USMax Planck Institute for Heart and Lung Research · DEUniversité Paris-Est Créteil · FRUniversity of California, Los Angeles · USWenzhou Medical University · CNWenzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBronchopulmonary dysplasia (BPD) is a lung disease of preterm born infants, characterized by alveolar simplification. MicroRNA (

resultsOur results showed that the expression level of

conclusionOur results suggest that down-regulation of

Indexed as

AnimalsBronchopulmonary DysplasiaCell ProliferationDisease Models, AnimalDown-RegulationFemaleMaleMiceMice, Inbred C57BLMicroRNAsSignal TransductionTransforming Growth Factor betaMicroRNAsMIRN154 microRNA, mouseTransforming Growth Factor betaalveolar simplificationAT2Caveolin1hyperoxiamiR-154Tgf-ß1

Identifiers

PMID32252341
PMCPMC7226730
OpenAlexW3014862270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.