Evidence map›Paper›PMID 32252280›Full record

ArticleMarine drugs2020

Marine-Inspired Bis-indoles Possessing Antiproliferative Activity against Breast Cancer; Design, Synthesis, and Biological Evaluation.

Wagdy M Eldehna, Ghada S Hassan, Sara T Al-Rashood, Hamad M Alkahtani, Abdulrahman A Almehizia, Ghada H Al-Ansary

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Bisindole Compounds-Synthesis and Medicinal Properties.Antibiotics (Basel, Switzerland) · 2024
    Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Wagdy M EldehnaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafr El-Sheikh 33516, Egypt.ORCID 0000-0001-6996-4017
Ghada S HassanDepartment of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.ORCID 0000-0003-3347-1047
Sara T Al-RashoodDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Hamad M AlkahtaniDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Abdulrahman A AlmehiziaDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.ORCID 0000-0001-8711-3873
Ghada H Al-AnsaryDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Ain Shams University, Cairo P.O. Box 11566, Egypt.
King Saud University · SAAin Shams University · EGKafrelsheikh University · EGMansoura University · EG

Funding

Deanship of Scientific Research, King Saud University Research Group Project no. RG-1439-65
6 · The paper itself

Abstract

Diverse indoles and bis-indoles extracted from marine sources have been identified as promising anticancer leads. Herein, we designed and synthesized novel bis-indole series

Indexed as

Antineoplastic AgentsApoptosisApoptosis Regulatory ProteinsBreast NeoplasmsCell CycleCell LineCell ProliferationCyclin-Dependent Kinase 2Drug DesignFemaleHumansImidazolesIndolesMCF-7 CellsMolecular StructureTumor Cells, CulturedAntineoplastic AgentsApoptosis Regulatory ProteinsCDK2 protein, humanCyclin-Dependent Kinase 2ImidazolesIndolestopsentintopsentin Aapoptosisbis-indolesbreast cancermarine-inspiredsynthesis

Identifiers

PMID32252280
PMCPMC7230731
OpenAlexW3014710988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.