Evidence map›Paper›PMID 32251638›Full record

ArticleThe Lancet. Infectious diseases2020

Baricitinib for COVID-19: a suitable treatment?

Ennio G Favalli, Martina Biggioggero, Gabriella Maioli, Roberto Caporali

Registry-linked trialAbstract readLetterComment
In one paragraph

Article in The Lancet. Infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04393051 (BARICIVID-19 STUDY), which is not on this map. Cited by 131 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04393051 phase2unknown statusnot on this map

BARICIVID-19 STUDY: MultiCentre, Randomised, Phase IIa Clinical Trial Evaluating Efficacy and Tolerability of Baricitinib as add-on Treatment of In-patients With COVID-19 Compared to Standard Therapy

TypeinterventionalSponsorAzienda Ospedaliero, Universitaria PisanaRan2020 to 2020Enrolled126ConditionsCovid-19, SARS-CoV 2, SARS PneumoniaArmsBaricitinib Oral Tablet
3 · Its place in the literature

Who cites it

131 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Is there any potential management against COVID-19? A systematic review and meta-analysis.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2020
    Pooled it
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  16. Small molecules in the treatment of COVID-19.Signal transduction and targeted therapy · 2022
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71 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Ennio G FavalliDivision of Clinical Rheumatology, ASST Gaetano Pini-CTO Institute, Milan 20122, Italy. Electronic address: ennio.favalli@gmail.com.
Martina BiggioggeroDivision of Clinical Rheumatology, ASST Gaetano Pini-CTO Institute, Milan 20122, Italy.
Gabriella MaioliDivision of Clinical Rheumatology, ASST Gaetano Pini-CTO Institute, Milan 20122, Italy; Department of Clinical Sciences and Community Health, Research Center for Adult and Pediatric Rheumatic Diseases, Università degli Studi di Milano, Milan, Italy.
Roberto CaporaliDivision of Clinical Rheumatology, ASST Gaetano Pini-CTO Institute, Milan 20122, Italy; Department of Clinical Sciences and Community Health, Research Center for Adult and Pediatric Rheumatic Diseases, Università degli Studi di Milano, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Antiviral AgentsCoronavirus InfectionsPandemicsPneumonia, ViralAnti-Inflammatory AgentsAzetidinesBetacoronavirusCOVID-19HumansPurinesPyrazolesSARS-CoV-2SulfonamidesAnti-Inflammatory AgentsAntiviral AgentsAzetidinesbaricitinibPurinesPyrazolesSulfonamides

Identifiers

PMID32251638
PMCPMC7270794

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.