Evidence map›Paper›PMID 32251579›Full record

ArticleJournal of the American Chemical Society2020

Access to Faster Eukaryotic Cell Labeling with Encoded Tetrazine Amino Acids.

Hyo Sang Jang, Subhashis Jana, Robert J Blizzard, Joseph C Meeuwsen, Ryan A Mehl

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 95 citations in OpenAlex.

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  9. An Expanded Toolbox for Versatile Chemical Editing of Adeno-Associated Virus.Angewandte Chemie (International ed. in English) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hyo Sang JangDepartment of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon 97331, United States.ORCID 0000-0003-0460-9924
Subhashis JanaDepartment of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon 97331, United States.
Robert J BlizzardDepartment of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon 97331, United States.
Joseph C MeeuwsenDepartment of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon 97331, United States.
Ryan A MehlDepartment of Biochemistry and Biophysics, Oregon State University, Corvallis, Oregon 97331, United States.ORCID 0000-0003-2932-4941
Oregon State University · US

Funding

Development of an improved core technology for efficient genetic code expansion in biomedical researchR01GM131168 · NIGMS · OREGON STATE UNIVERSITY · PI MEHL, RYAN A · 2019 to 2021
$1.1M
NIGMS NIH HHS R01 GM131168
6 · The paper itself

Abstract

Labeling of biomolecules in live eukaryotic cells has been limited by low component stability and slow reaction rates. We show that genetically encoded tetrazine amino acids in proteins reach reaction rates of 8 × 10

Indexed as

Amino AcidsEukaryotic CellsAmino Acids

Identifiers

PMID32251579
PMCPMC7771912
OpenAlexW3015152715

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.