ArticleNature neuroscience2020
Hippocampal neurons represent events as transferable units of experience.
Article in Nature neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 66 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
66 citing papers in PubMed.
- Early Spatial and Contextual Coding Deficits in Hippocampal CA1 Precede Performance Decline in an Alzheimer's Disease Model.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Prefrontal-thalamic goal states organize spatially aligned hippocampal maps.Nature communications · 2026Article
- A deep reinforcement learning account of competition and integration of visual and goal vector signals for spatial navigation.Scientific reports · 2026Article
- The hippocampus as a generative model.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Review
- GATE: Adaptive learning with working memory by information gating in multi-lamellar hippocampal formation.PLoS computational biology · 2026Article
- Article
- Retrospective duration judgments of naturalistic events depend on memories of event boundaries.Psychonomic bulletin & review · 2026Article
- Prefrontal Default Mode Network Interactions with Posterior Hippocampus during Exploration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- The Primate Hippocampus Constructs a Temporal Scaffold Anchored to Behavioral Events.bioRxiv : the preprint server for biology · 2025Article
- Three types of remapping with linear decoders: A population-geometric perspective.PLoS computational biology · 2025Article
- Boundaries in the eyes: Measure event segmentation during naturalistic video watching using eye tracking.Behavior research methods · 2025Article
- Three types of remapping with linear decoders: a population-geometric perspective.bioRxiv : the preprint server for biology · 2025Article
- Article
- Constructing future behavior in the hippocampal formation through composition and replay.Nature neuroscience · 2025Article
- Thinking as Analogy-Making: Toward a Neural Process Account of General Intelligence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- Article
- Acetylcholine modulates prefrontal outcome coding during threat learning under uncertainty.eLife · 2025Article
- Article
- Large language models can segment narrative events similarly to humans.Behavior research methods · 2025Article
- Multiplexing of temporal and spatial information in the lateral entorhinal cortex.Nature communications · 2024Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
4 authors.
Funding
Abstract
The brain codes continuous spatial, temporal and sensory changes in daily experience. Recent studies suggest that the brain also tracks experience as segmented subdivisions (events), but the neural basis for encoding events remains unclear. Here, we designed a maze for mice, composed of four materially indistinguishable lap events, and identify hippocampal CA1 neurons whose activity are modulated not only by spatial location but also lap number. These 'event-specific rate remapping' (ESR) cells remain lap-specific even when the maze length is unpredictably altered within trials, which suggests that ESR cells treat lap events as fundamental units. The activity pattern of ESR cells is reused to represent lap events when the maze geometry is altered from square to circle, which suggests that it helps transfer knowledge between experiences. ESR activity is separately manipulable from spatial activity, and may therefore constitute an independent hippocampal code: an 'event code' dedicated to organizing experience by events as discrete and transferable units.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.