Pyroptosis heats tumour immunity.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

16 citing papers in PubMed.

1. GSDME acts as an epigenetic modifier to promote melanoma development via centriole biogenesis regulator PLK4.Cell death and differentiation · 2026
   Article
2. Cuproptosis: a novel therapeutic mechanism in lung cancer.Cancer cell international · 2025
   Review
3. [Research Progress on the Role of GSDME-mediated Pyroptosis in the Treatment of 
Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2024
   Review
4. Research Progress on Pyroptosis in Hematological Malignancies.Current treatment options in oncology · 2023
   Review
5. Dual-Pronged Attack: pH-Driven Membrane-Anchored NIR Dual-Type Nano-Photosensitizer Excites Immunogenic Pyroptosis and Sequester Immune Checkpoint for Enhanced Prostate Cancer Photo-Immunotherapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
   Article
6. CTLA-4 blockade induces tumor pyroptosis via CD8Molecular therapy : the journal of the American Society of Gene Therapy · 2023
   Article
7. The Therapeutic Potential of Pyroptosis in Melanoma.International journal of molecular sciences · 2023
   Review
8. Effect of regulatory cell death on the occurrence and development of head and neck squamous cell carcinoma.Biomarker research · 2023
   Review
9. Pyroptosis patterns of colon cancer could aid to estimate prognosis, microenvironment and immunotherapy: evidence from multi-omics analysis.Aging · 2022
   Article
10. Pyroptosis correlates with tumor immunity and prognosis.Communications biology · 2022
    Article
11. Emerging mechanisms of pyroptosis and its therapeutic strategy in cancer.Cell death discovery · 2022
    Review
12. Myoglobin promotes macrophage polarization to M1 type and pyroptosis via the RIG-I/Caspase1/GSDMD signaling pathway in CS-AKI.Cell death discovery · 2022
    Article
13. Prognosis and immune features of pyroptosis-related RNA patterns in low-grade glioma.Frontiers in oncology · 2022
    Article
14. Immunogenic Cell Death and Role of Nanomaterials Serving as Therapeutic Vaccine for Personalized Cancer Immunotherapy.Frontiers in immunology · 2022
    Review
15. Disease markers · 2022
    Article
16. Bioinformatic Analysis of Prognostic Value of Pyroptosis-Related Genes and Its Effect on Immune Cell Infiltration in Pancreatic Adenocarcinoma.International journal of general medicine · 2022
    Article

Corrections and comments

• Comment on
  A bioorthogonal system reveals antitumour immune function of pyroptosis.2020
• Comment on
  Gasdermin E suppresses tumour growth by activating anti-tumour immunity.2020

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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