Evidence map›Paper›PMID 32251368›Full record

Observational studySpinal cord2020

Gait rehabilitation in persons with spinal cord injury using innovative technologies: an observational study.

Giulia Stampacchia, Matteo Olivieri, Alessandro Rustici, Carla D'Avino, Adriana Gerini, Stefano Mazzoleni

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Spinal cord, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 4 pooled it
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 4 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  5. Article
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  7. Article
  8. Biomaterials and cell-based therapy post spinal cord injury.Journal of translational medicine · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Giulia StampacchiaSpinal Cord Unit, Pisa University Hospital, Pisa, Italy. g.stampacchia@ao-pisa.toscana.it.
Matteo OlivieriSpinal Cord Unit, Pisa University Hospital, Pisa, Italy.
Alessandro RusticiSpinal Cord Unit, Pisa University Hospital, Pisa, Italy.
Carla D'AvinoSpinal Cord Unit, Pisa University Hospital, Pisa, Italy.
Adriana GeriniSpinal Cord Unit, Pisa University Hospital, Pisa, Italy.
Stefano MazzoleniThe BioRobotics Institute, Scuola Superiore Sant'Anna, Pisa, Italy.ORCID http://orcid.org/0000-0002-9528-3239
Scuola Superiore Sant'Anna · ITUniversity of Pisa · IT

Funding

Ministero della Salute (Ministry of Health, Italy) RF-2011-02346770
6 · The paper itself

Abstract

STUDY

designProspective, quasi-experimental study, pre- and post-design, single arm study.

objectivesInvestigate whether persons affected by SCI can safely experience walking function using Robotic Exoskeletons and Functional Electrical Stimulation (FES).

settingInpatient

methods52 persons with SCI were recruited (36 completed the protocol) and assigned to one of two groups based on their Lower Limb Motor Scores (LEMS): Group A: LEMS ≥ 10 and Group B: LEMS < 10. Participants in Group A (n = 19) underwent 20 sessions of Robot-Assisted Gait Training (RAGT) on a treadmill followed by 20 sessions of FES during Overground Gait (FES-OG). Participants in Group B (n = 17) received 20 sessions of FES-cycling followed by 20 sessions of overground RAGT. The main outcome measures were: WISCI-II, 10MWT, 6MWT, TUG and SCIM-II.

results36 persons completed the study with no complications; only 4 of the 16 dropped out because of mild complications during the RAGT. Participants in Group A exhibited significant improvements in WISCI-II, 10MWT, 6MWT and TUG (p < 0.05), while those in Group B did not significantly improve their gait function but their walking velocity and resistance with the assistance of the robotic exoskeleton increased. SCIM-II scores increased followed therapy only in Group A.

conclusionsPersons affected by SCI can safely experience their walking function with RAGT and FES therapy; only few mild complications were observed. Our data provides initial evidence of the potential value of these technologies, especially in persons with SCI having LEMS > 10.

Indexed as

Electric Stimulation TherapyExercise TherapyExoskeleton DeviceNeurological RehabilitationOutcome and Process Assessment, Health CareAdultCombined Modality TherapyFemaleGait Disorders, NeurologicHumansMaleMiddle AgedProspective StudiesSpinal Cord Injuries

Identifiers

PMID32251368
OpenAlexW3015064521

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.