Evidence map›Paper›PMID 32251320›Full record

ArticleScientific reports2020

Maternal obesity and severe pre-eclampsia among immigrant women: a mediation analysis.

Ayesha Siddiqui, Catherine Deneux-Tharaux, Dominique Luton, Thomas Schmitz, Laurent Mandelbrot, Candice Estellat, Elizabeth A Howell, Babak Khoshnood, Nathalie Bertille, Elie Azria

Open access · goldAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

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  12. The Distribution of Foxp3 and CD68 in Preeclamptic and Healthy Placentas: A Histomorphological Evaluation.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Ayesha SiddiquiINSERM U1153 Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Center for Epidemiology and Statistics Sorbonne Paris Cité, Risks in Pregnancy DHU, Paris Descartes University, Paris, France. ayesha.siddiqui@inserm.fr.ORCID http://orcid.org/0000-0002-7457-6745
Catherine Deneux-TharauxINSERM U1153 Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Center for Epidemiology and Statistics Sorbonne Paris Cité, Risks in Pregnancy DHU, Paris Descartes University, Paris, France.
Dominique LutonDepartment of Obstetrics and Gynecology, Beaujon-Bichat Hospital, University Hospital Department (DHU) Risks in Pregnancy, Paris Diderot University, Paris, France.
Thomas SchmitzDepartment of Obstetrics and Gynecology, Robert Debré Hospital, Paris Diderot University, Paris, France.
Laurent MandelbrotDepartment of Obstetrics and Gynecology, Louis Mourier Hospital, University Hospital Department (DHU) Risks in Pregnancy, Paris Diderot University, Colombes, France.
Candice EstellatPitié-Salpêtrière Hospital - Charles Foix; Department of Biostatistics, Public Health and Medical Information, Clinical Research Unit, Pharmacoepidemiology Center (Céphépi), Sorbonne University; INSERM UMR-S 1136 - Pierre Louis Institute of Epidemiology and Public Health, Paris, France.
Elizabeth A HowellDepartment of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Babak KhoshnoodINSERM U1153 Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Center for Epidemiology and Statistics Sorbonne Paris Cité, Risks in Pregnancy DHU, Paris Descartes University, Paris, France.
Nathalie BertilleINSERM U1153 Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Center for Epidemiology and Statistics Sorbonne Paris Cité, Risks in Pregnancy DHU, Paris Descartes University, Paris, France.
Elie AzriaINSERM U1153 Obstetrical, Perinatal and Pediatric Epidemiology Research Team (EPOPé), Center for Epidemiology and Statistics Sorbonne Paris Cité, Risks in Pregnancy DHU, Paris Descartes University, Paris, France.
Inserm · FRUniversité Paris Cité · FRDélégation Paris 5 · FRIcahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We investigated the extent to which pre-pregnancy obesity mediates the association between maternal place of birth and severe pre-eclampsia in the PreCARE cohort of pregnant women in Paris (n = 9,579). Adjusted path analysis logistic regression models were used to assess the role of pre-pregnancy obesity as a mediator in the association between maternal place of birth and the development of severe pre-eclampsia. We calculated 1. adjusted odds ratios and 95% confidence intervals for the total exposure-outcome association and for the direct and indirect/obesity-mediated components 2. the indirect/obesity-mediated effect. Ninety-five (0.99%) women developed severe pre-eclampsia, 47.6% were non-European immigrants, 16.3% were born in Sub-Saharan Africa, and 12.6% were obese (BMI > = 30 kg/m

Indexed as

Emigrants and ImmigrantsAdultAfrica, NorthernAfrica South of the SaharaEuropeFemaleHumansMaternal AgeParisPoverty AreasPre-EclampsiaPregnancyPregnancy in ObesityRiskUrban PopulationYoung Adult

Identifiers

PMID32251320
PMCPMC7089990
OpenAlexW3012633628

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.