Evidence map›Paper›PMID 32250712›Full record

ArticleRNA biology2020

The large repertoire of 2'-O-methylation guided by C/D snoRNAs on Trypanosoma brucei rRNA.

K Shanmugha Rajan, Yinzhou Zhu, Katerina Adler, Tirza Doniger, Smadar Cohen-Chalamish, Ankita Srivastava, Moran Shalev-Benami, Donna Matzov, Ron Unger, Christian Tschudi and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in RNA biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. SnoRNA Expression and RNA 2'-O-Methylation inbioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Ribosome Specialization in Protozoa Parasites.International journal of molecular sciences · 2023
    Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Transcriptome-Wide Identification of 2'-O-Methylation Sites with RibOxi-Seq.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

K Shanmugha RajanThe Mina and Everard Goodman Faculty of Life Sciences and Advanced Materials and Nanotechnology Institute, Bar-Ilan University , Ramat-Gan, Israel.ORCID 0000-0003-4826-9802
Yinzhou ZhuDepartment of Genetics and Genome Sciences, UConn Health , Farmington, CT, USA.ORCID 0000-0003-0043-1321
Katerina AdlerThe Mina and Everard Goodman Faculty of Life Sciences and Advanced Materials and Nanotechnology Institute, Bar-Ilan University , Ramat-Gan, Israel.ORCID 0000-0001-5769-8284
Tirza DonigerThe Mina and Everard Goodman Faculty of Life Sciences and Advanced Materials and Nanotechnology Institute, Bar-Ilan University , Ramat-Gan, Israel.ORCID 0000-0001-6708-8404
Smadar Cohen-ChalamishThe Mina and Everard Goodman Faculty of Life Sciences and Advanced Materials and Nanotechnology Institute, Bar-Ilan University , Ramat-Gan, Israel.
Ankita SrivastavaDepartment of Genetics and Genome Sciences, UConn Health , Farmington, CT, USA.
Moran Shalev-BenamiDepartment of Structural Biology, Weizmann Institute of Science , Rehovot, Israel.
Donna MatzovDepartment of Structural Biology, Weizmann Institute of Science , Rehovot, Israel.ORCID 0000-0003-2600-9727
Ron UngerThe Mina and Everard Goodman Faculty of Life Sciences and Advanced Materials and Nanotechnology Institute, Bar-Ilan University , Ramat-Gan, Israel.ORCID 0000-0003-4153-3922
Christian TschudiDepartmentof Epidemiology and Microbial Diseases, Yale School of Public Health , New Haven, CT, USA.
Arthur GünzlDepartment of Genetics and Genome Sciences, UConn Health , Farmington, CT, USA.
Gordon G CarmichaelDepartment of Genetics and Genome Sciences, UConn Health , Farmington, CT, USA.ORCID 0000-0002-0379-6580
Shulamit MichaeliThe Mina and Everard Goodman Faculty of Life Sciences and Advanced Materials and Nanotechnology Institute, Bar-Ilan University , Ramat-Gan, Israel.ORCID 0000-0002-9895-0439
Bar-Ilan University · ILUConn Health · USWeizmann Institute of Science · ILYale University · US

Funding

TRANSCRIPTION AND RNA PROCESSING IN TRYPANOSOMESR01AI028798 · NIAID · YALE UNIVERSITY · PI TSCHUDI, CHRISTIAN · 1990 to 2020
$10.9M
Mechanism of Infectivity Acquisition in African TrypanosomesR01AI110325 · NIAID · YALE UNIVERSITY · PI TSCHUDI, CHRISTIAN · 2014 to 2023
$4.4M
The basic functions of Trypanosoma brucei's two intronsR21AI142149 · NIAID · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI GUNZL, ARTHUR · 2019 to 2020
$450k
Genomewide mapping of sites of RNA 2'-0-methylation in Prader-Willi SyndromeR21MH110955 · NIMH · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI CARMICHAEL, GORDON G · 2017 to 2018
$431k
NIAID NIH HHS R01 AI028798NIAID NIH HHS R01 AI110325NIAID NIH HHS R21 AI142149NIMH NIH HHS R21 MH110955
6 · The paper itself

Abstract

The parasite

Indexed as

RNA, ProtozoanRNA, RibosomalComputational BiologyConnectomeGene Expression ProfilingNucleic Acid ConformationRNA, Small NucleolarTranscriptomeTrypanosoma brucei bruceiRNA, ProtozoanRNA, RibosomalRNA, Small Nucleolar2ʹ-OMe-seqRiboMeth-seqRibOxi-seqrRNAsnoRNATrypanosomes

Identifiers

PMID32250712
PMCPMC7549662
OpenAlexW3014228495

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.