Evidence map›Paper›PMID 32250170›Full record

ArticleExpert opinion on biological therapy2020

Will plant-made biopharmaceuticals play a role in the fight against COVID-19?

Sergio Rosales-Mendoza

Abstract readEditorial
In one paragraph

Article in Expert opinion on biological therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Generation of multi-layered protein bodies inFrontiers in plant science · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Plant-derived natural products for drug discovery: current approaches and prospects.The Nucleus : an international journal of cytology and allied topics · 2022
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. COVID-19 vaccines and nanomedicine.International journal of dermatology · 2021
    Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. COVID-19 Crisis: How Can Plant Biotechnology Help?Plants (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Sergio Rosales-MendozaFacultad De Ciencias Químicas, Universidad Autónoma De San Luis Potosí, San Luis Potosí, México.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the dramatic impact of the COVID-19 pandemic, it is imperative to divulge all the available technologies with the potential to fight against this virus. Plant biotechnology offers potential solutions to this pandemic through the development of low-cost vaccines and antibodies useful for therapy, prophylaxis, and diagnosis. The technology to produce plant-made biopharmaceuticals is already established; two examples of these are: a therapeutic enzyme that has entered the market and the influenza vaccines that are currently under clinical trials with encouraging results. Thus far, some companies have started developing anti-COVID-19 antibodies and vaccines. In particular, plant-made antibodies might be timely produced and approved for human use in the short term, while the development of vaccines will take longer time (clinical evaluations could be concluded by the end of 2021); nonetheless, the candidates obtained will be valuable tools for future outbreaks. The key aspects that will define the exploitation of this technology in the fight against COVID-19 are discussed.

Indexed as

Molecular FarmingPlants, Genetically ModifiedAntibodies, ViralBetacoronavirusBiological ProductsBiotechnologyCoronavirus InfectionsCOVID-19COVID-19 VaccinesHumansPandemicsPneumonia, ViralSARS-CoV-2Viral VaccinesAntibodies, ViralBiological ProductsCOVID-19 VaccinesViral VaccinesbiomanufacturingCOVID-19 vaccinemucosal immunizationplantibodySARS-CoV-2 virus

Identifiers

PMID32250170
PMCPMC7157952

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.