Evidence map›Paper›PMID 32249562›Full record

ArticleEnvironmental science & technology2020

Nontarget Screening of Per- and Polyfluoroalkyl Substances Binding to Human Liver Fatty Acid Binding Protein.

Diwen Yang, Jiajun Han, David Ross Hall, Jianxian Sun, Jesse Fu, Steven Kutarna, Keith A Houck, Carlie A LaLone, Jon A Doering, Carla A Ng and 1 more

Open access · greenAbstract read
In one paragraph

Article in Environmental science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 90 citations in OpenAlex.

  1. Review
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  7. Observational
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  15. Effects of PFAS on human liver transporters: implications for health outcomes.Toxicological sciences : an official journal of the Society of Toxicology · 2024
    Review
  16. Article
  17. Article
  18. Sunrise of PFAS Replacements: A Perspective on Fluorine-Free Foams.ACS sustainable chemistry & engineering · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Diwen YangDepartment of Chemistry, University of Toronto, Toronto M5S 3H6, ON, Canada.
Jiajun HanDepartment of Chemistry, University of Toronto, Toronto M5S 3H6, ON, Canada.
David Ross HallDepartment of Chemistry, University of Toronto, Toronto M5S 3H6, ON, Canada.
Jianxian SunDepartment of Chemistry, University of Toronto, Toronto M5S 3H6, ON, Canada.
Jesse FuDepartment of Chemistry, University of Toronto, Toronto M5S 3H6, ON, Canada.
Steven KutarnaDepartment of Chemistry, University of Toronto, Toronto M5S 3H6, ON, Canada.
Keith A HouckCenter for Computational Toxicology and Exposure, Office of Research and Development, United States Environmental Protection Agency, Research Triangle Park, Durham, North Carolina 27711, United States.
Carlie A LaLoneGreat Lakes Toxicology and Ecology Division, U.S. Environmental Protection Agency, Duluth, Minnesota 55804, United States.ORCID 0000-0003-3174-1314
Jon A DoeringGreat Lakes Toxicology and Ecology Division, U.S. Environmental Protection Agency, Duluth, Minnesota 55804, United States.ORCID 0000-0001-6866-6456
Carla A NgDepartment of Civil & Environmental Engineering, University of Pittsburgh, 3700 O'Hara St, Pittsburgh, Pennsylvania 15261, United States.
Hui PengDepartment of Chemistry, University of Toronto, Toronto M5S 3H6, ON, Canada.ORCID 0000-0002-2777-0588
University of Toronto · CAEnvironmental Protection Agency · USUniversity of Pittsburgh · US

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

More than 1000 per- and polyfluoroalkyl substances (PFASs) have been discovered by nontarget analysis (NTA), but their prioritization for health concerns is challenging. We developed a method by incorporating size-exclusion column co-elution (SECC) and NTA, to screen PFASs binding to human liver fatty acid binding protein (

Indexed as

Fatty Acid-Binding ProteinsFluorocarbonsHumansWaterWater Pollutants, ChemicalFatty Acid-Binding ProteinsFluorocarbonsWaterWater Pollutants, Chemical

Identifiers

PMID32249562
PMCPMC7477755
OpenAlexW3015134458

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.