Evidence map›Paper›PMID 32249504›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2020

Association between pulse pressure and aortic calcification: Findings from the National Health and Nutrition Examination Survey 2013-2014.

Kevin S Heffernan, Tiago V Barreira

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Association of Dietary Potassium Intake With Abdominal Aortic Calcification and Pulse Pressure in US Adults.Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Pulse pressure and aortic calcification: Did we learn something?Journal of clinical hypertension (Greenwich, Conn.) · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kevin S HeffernanDepartment of Exercise Science, Syracuse University, Syracuse, NY, USA.ORCID 0000-0002-3499-1477
Tiago V BarreiraDepartment of Exercise Science, Syracuse University, Syracuse, NY, USA.
Syracuse University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dual-energy X-ray absorptiometry (DXA) is a low-cost, minimal radiation technique commonly used to assess bone density and body composition that can also provide a measure of abdominal aortic calcification (AAC). We examined the association between pulse pressure (PP) and DXA-derived AAC in a nationally representative sample of US adults. Analyses were performed in 2,478 adults from the 2013-2014 NHANES cycle. AAC scores were calculated using a validated 24-point scale from thoraco-lumbar spine images (scored 1-6 across four vertebral heights from L1-L4 for both anterior and posterior aortic walls). We examined PP as a predictor of both the presence (dichotomous) and magnitude (continuous) of AAC in age-stratified analyses (<60 years of age and ≥60 years of age) adjusting for traditional cardiovascular disease risk factors, sex, mean arterial pressure and additionally for age and antihypertensive medication. The prevalence of AAC was 25.5%. PP was a predictor of the presence of AAC in fully adjusted models in adults <60 years of age (OR 1.31, P < .05) and ≥60 years of age (OR 1.33, P < .05). PP was also associated with the magnitude of AAC in the overall sample but did not retain significance after separating by age-groups and additionally adjusting for antihypertensive medication. In conclusion, PP is associated with the presence of AAC as measured by DXA in a nationally representative sample of US adults.

Indexed as

Blood PressureAorta, AbdominalBone DensityHumansHypertensionMiddle AgedNutrition SurveysRisk FactorsVascular Calcificationblood pressureDXANHANESvascular stiffness

Identifiers

PMID32249504
PMCPMC8030045
OpenAlexW3014393501

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.