ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2020
Pediatric septal dysembryoplastic neuroepithelial tumor (sDNT): case-based update.
Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Myxoid Glioneuronal Tumours with PDGFRA p.K385 Mutations Causing Hydrocephalus and Successfully Treated with Neuroendoscopic Surgery: A Case Report and Literature Review.NMC case report journal · 2025Article
- Article
- Temporal lobe myxoid glioneuronal tumor, PDGFRA p.K385L-mutant with DNA methylation confirmation.Brain pathology (Zurich, Switzerland) · 2022Article
- Intraventricular dysembryoplastic neuroepithelial tumor in the temporal horn with Broad involvement of the ependyma.Clinical case reports · 2021Article
- Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to review a case of a septal dysembryoplastic neuroepithelial tumor (sDNT) and compare it to cases reported in the current literature.
methodsWe review a case of sDNT and compare with 7 other previously noted cases in the literature.
resultsThe mainstay treatment is gross total resection, and most patients achieve full clinical resolution. Septal dysembryoplastic neuroepithelial tumor (sDNT) is a rare pediatric disease most commonly presenting as intractable epilepsy or headache. sDNT has been recognized as a genotypically distinct entity from DNT. A high frequency (~ 80%) of mutations of platelet-derived growth factor receptor A (PDGFRA) has been isolated in sDNT and could form the basis for future therapy. MRI is most commonly used to radiographically diagnose the disease and usually demonstrates a lobular interventricular mass involving the septum, potentially extending to the third ventricle.
conclusionsOur case and literature review validates endoscopic biopsy as a diagnostic and therapeutic intervention.
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Registered trials
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