ArticleCancer discovery2020
Combined Cohesin-RUNX1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes.
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Article in Cancer discovery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers.
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61citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
What it found
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Who cites it
61 citing papers in PubMed, 81 citations in OpenAlex.
- Article
- The Runx1-Gata2 axis: epigenetic architecture of lineage fate.Molecular biology reports · 2026Review
- The effect of cohesin mutations on HLA-class II expression in the myeloid leukemia of Down syndrome.Leukemia · 2026Article
- Article
- Personalized reference genome-based pipeline reveals comprehensive haplotype-resolved views of cancer genomes.bioRxiv : the preprint server for biology · 2026Article
- [Clinical characteristics and prognosis of myelodysplastic neoplasms with GATA2 mutations].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2026Article
- Distinct routes of clonal progression in SF3B1-mutant myelodysplastic syndromes.Blood advances · 2025Article
- JMJD1C forms condensate to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cells.Protein & cell · 2025Article
- Myelodysplastic Neoplasms (MDS): Pathogenesis and Therapeutic Prospects.Biomolecules · 2025Review
- SMC2 and Condensin II Subunits Are Essential for the Development of Hematopoietic Stem and Progenitor Cells in Zebrafish.Journal of cellular physiology · 2025Article
- Liquid condensates: a new barrier to loop extrusion?Cellular and molecular life sciences : CMLS · 2025Review
- Emerging roles of cohesin-STAG2 in cancer.Oncogene · 2025Review
- A CML Patient Carrying BCR::ABL1 Splicing Variants Did Not Experience Blast Crisis for 15 Years without Responding to Various TKIs.Internal medicine (Tokyo, Japan) · 2025Article
- ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF.Molecular cell · 2025Article
- The Functions and Mechanisms of the Cohesin Complex in Regulating the Fate Determinations of Stem Cells.Research (Washington, D.C.) · 2025Review
- Untangling the loops ofLeukemia & lymphoma · 2025Review
- STAG2 loss in Ewing sarcoma alters enhancer-promoter contacts dependent and independent of EWS::FLI1.EMBO reports · 2024Article
- Cohesin mutations in acute myeloid leukemia.Leukemia · 2024Review
- Subunit-specific analysis of cohesin-mutant myeloid malignancies reveals distinct ontogeny and outcomes.Leukemia · 2024Article
- Cohesin composition and dosage independently affect early development in zebrafish.Development (Cambridge, England) · 2024Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
36 authors at 12 institutions in 4 countries.
Yotaro OchiDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0001-8472-6164
Ayana KonDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Toyonori SakataLaboratory of Genome Structure and Function, Research Division for Quantitative Life Sciences, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan.
Masahiro M NakagawaDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Naotaka NakazawaInstitute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Kyoto, Japan.ORCID 0000-0002-8695-4344
Masanori KakutaLaboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.ORCID 0000-0003-4978-2827
Keisuke KataokaDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Haruhiko KosekiLaboratory for Developmental Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.
Manabu NakayamaLaboratory of Medical Omics Research, Department of Frontier Research and Development, Kazusa DNA Research Institute, Kisarazu, Japan.
Daisuke MorishitaChordia Therapeutics Inc., Kanagawa, Japan.
Tatsuaki TsuruyamaDepartment of Drug and Discovery Medicine, Pathology Division, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Ryunosuke SaikiDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Akinori YodaDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Rurika OkudaDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tetsuichi YoshizatoDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Kenichi YoshidaDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yusuke ShiozawaDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yasuhito NannyaDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Shinichi KotaniDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Yasunori KogureDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.ORCID 0000-0003-1158-5131
Nobuyuki KakiuchiDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Tomomi NishimuraDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Hideki MakishimaDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Luca MalcovatiDepartment of Molecular Medicine, University of Pavia, Pavia, Italy.
Akihiko YokoyamaTsuruoka Metabolomics Laboratory, National Cancer Center, Yamagata, Japan.ORCID 0000-0002-5639-8068
Kengo TakeuchiPathology Project for Molecular Targets, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.
Eiji SugiharaResearch and Development Center for Precision Medicine, University of Tsukuba, Ibaraki, Japan.ORCID 0000-0002-3233-1045
Taka-Aki SatoResearch and Development Center for Precision Medicine, University of Tsukuba, Ibaraki, Japan.
Masashi SanadaDepartment of Advanced Diagnosis, Clinical Research Center, National Hospital Organization Nagoya Medical Center, Nagoya, Japan.
Akifumi Takaori-KondoDepartment of Hematology and Oncology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
Mario CazzolaDepartment of Molecular Medicine, University of Pavia, Pavia, Italy.ORCID 0000-0001-6984-8817
Mineko KengakuInstitute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University, Kyoto, Japan.
Satoru MiyanoLaboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Katsuhiko ShirahigeLaboratory of Genome Structure and Function, Research Division for Quantitative Life Sciences, Institute for Quantitative Biosciences, The University of Tokyo, Tokyo, Japan.
Hiroshi I SuzukiDavid H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts. sogawa-tky@umin.ac.jp hisuzuki-tky@umin.ac.jp.ORCID 0000-0003-4682-5086
Seishi OgawaDepartment of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan. sogawa-tky@umin.ac.jp hisuzuki-tky@umin.ac.jp.ORCID 0000-0002-7778-5374
Kyoto University · JPQuantitative BioSciences · USTokyo Medical University · JPUniversity of Pavia · ITUniversity of Tsukuba · JPAcorda Therapeutics (United States) · USJapanese Foundation For Cancer Research · JPKazusa DNA Research Institute · JPMassachusetts Institute of Technology · USNagoya Medical Center · JPNational Institute of Technology, Tsuruoka College · JPRIKEN Center for Integrative Medical Sciences · JP
Funding
VIRUS PRODUCTION COREP30CA014051 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI MATTHEW G. VANDER HEIDEN · 1985 to 2026
$93.9MUSE OF RETROVIRUS PROMOTER TRAP VECTORS TO IDENTIFY ONCOGENES AND ANTI-ONCOGENESP01CA042063 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI JACKS, TYLER E. · 1986 to 2021
$30.5MREGULATION OF MRNA PROCESSINGR01GM034277 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SHARP, PHILLIP A · 1985 to 2021
$8.0MStress and Proliferation States Impact MicroRNA-Mediated Regulation in CancerR01CA133404 · NCI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI SHARP, PHILLIP A · 2008 to 2017
$4.6MNCI NIH HHS P01 CA042063NCI NIH HHS P30 CA014051NCI NIH HHS R01 CA133404NIGMS NIH HHS R01 GM034277
Abstract
PubMed holds no abstract for this paper.
Indexed as
AnimalsCell Cycle ProteinsChromatinChromosomal Proteins, Non-HistoneCohesinsCore Binding Factor Alpha 2 SubunitGene Expression RegulationHumansMiceMice, KnockoutMyelodysplastic SyndromesCell Cycle ProteinsChromatinChromosomal Proteins, Non-HistoneCohesinsCore Binding Factor Alpha 2 SubunitRUNX1 protein, human
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.