Evidence map›Paper›PMID 32249063›Full record

ArticleTrends in immunology2020

Neutralizing Antibodies against SARS-CoV-2 and Other Human Coronaviruses.

Shibo Jiang, Christopher Hillyer, Lanying Du

Erratum issued Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Trends in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT04412486 (An Open Label Trial of Transfusion of COVID-19 Convalescent Plasma), which is not on this map. Cited by 545 papers.

0numbers the graph read from it
0cells of the map it votes in
545citing papers in PubMed
22.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04412486 early_phase1completednot on this map

An Open Label Trial of Transfusion of COVID-19 Convalescent Plasma (CCP) to Patients With Moderate to Severe COVID-19

TypeinterventionalSponsorGailen D. Marshall Jr., MD PhDRan2020 to 2023Enrolled86ConditionsCOVID-19ArmsCOVID Convalescent Plasma
3 · Its place in the literature

Who cites it

545 citing papers in PubMed, 935 citations in OpenAlex.

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  6. Mapping SARS-CoV-2 Nucleocapsid Function with Nanobodies.bioRxiv : the preprint server for biology · 2026
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485 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 2 countries.

Shibo JiangLindsley F. Kimball Research Institute, New York Blood Center, New York, NY, USA; Key Laboratory of Medical Molecular Virology (MOE/NHC/CAMS), School of Basic Medical Sciences, Fudan University, Shanghai, China.
Christopher HillyerLindsley F. Kimball Research Institute, New York Blood Center, New York, NY, USA.
Lanying DuLindsley F. Kimball Research Institute, New York Blood Center, New York, NY, USA. Electronic address: ldu@nybc.org.
New York Blood Center · US

Funding

Structure-based design of coronavirus subunit vaccinesR01AI139092 · NIAID · NEW YORK BLOOD CENTER · PI DU, LANYING · 2018 to 2022
$4.2M
Rational design and evaluation of novel mRNA vaccines against MERS-CoVR01AI137472 · NIAID · NEW YORK BLOOD CENTER · PI DU, LANYING · 2018 to 2022
$4.1M
Novel nanobodies to prevent and treat SARS-CoV-2 and other pathogenic human coronavirusesR01AI157975 · NIAID · NEW YORK BLOOD CENTER · PI DU, LANYING, LI, FANG · 2020 to 2025
$3.9M
NIAID NIH HHS R01 AI137472NIAID NIH HHS R01 AI139092NIAID NIH HHS R01 AI157975
6 · The paper itself

Abstract

Coronavirus (CoV) disease 2019 (COVID-19) caused by severe acute respiratory syndrome (SARS)-CoV-2 (also known as 2019-nCoV) is threatening global public health, social stability, and economic development. To meet this challenge, this article discusses advances in the research and development of neutralizing antibodies (nAbs) for the prevention and treatment of infection by SARS-CoV-2 and other human CoVs.

Indexed as

Antibodies, NeutralizingAntibodies, ViralBetacoronavirusCoronavirusCoronavirus InfectionsCOVID-19HumansPandemicsPneumonia, ViralResearchSARS-CoV-2Antibodies, NeutralizingAntibodies, Viralhuman coronavirusesMERS-CoVneutralizing antibodiesSARS-CoVSARS-CoV-2

Identifiers

PMID32249063
PMCPMC7129017
OpenAlexW3013525829

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.