Evidence map›Paper›PMID 32249004›Full record

ArticleWomen's health issues : official publication of the Jacobs Institute of Women's Health

Sexual Orientation Differences in Cervical Cancer Prevention among a Cohort of U.S. Women.

Alexa L Solazzo, Madina Agénor, S Bryn Austin, Jorge E Chavarro, Brittany M Charlton

Abstract read
In one paragraph

Article in Women's health issues : official publication of the Jacobs Institute of Women's Health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexa L SolazzoDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Division of Adolescent, Young Adult Medicine, Boston Children's Hospital, Boston, Massachusetts. Electronic address: alexa.solazzo@gmail.com.
Madina AgénorDepartment of Community Health, Tufts University, Boston, Massachusetts; Tufts Clinical and Translational Science Institute, Tufts University, Boston, Massachusetts; The Fenway Institute, Fenway Health, Boston, Massachusetts.
S Bryn AustinDivision of Adolescent, Young Adult Medicine, Boston Children's Hospital, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts; Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Jorge E ChavarroDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, Massachusetts.
Brittany M CharltonDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts; Division of Adolescent, Young Adult Medicine, Boston Children's Hospital, Boston, Massachusetts; Department of Pediatrics, Harvard Medical School, Boston, Massachusetts; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

Funding

Integrating lifecourse approaches, biologic and digital phenotypes in support of heart and lung disease epidemiologic researchU01HL145386 · NHLBI · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI CHAVARRO, JORGE EDUARDO, MANSON, JOANN ELISABETH · 2019 to 2025
$17.8M
Training Program in Cancer EpidemiologyT32CA009001 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI A. Heather Eliassen, Meir Stampfer · 1985 to 2026
$17.3M
Sexual Orientation and Obesity: Test of a Gendered Biopsychosocial ModelR01HD066963 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI AUSTIN, S BRYN · 2011 to 2015
$3.5M
Causes and Impact of Minority Stress on Health and Development in YouthR01HD057368 · NICHD · BRIGHAM AND WOMEN'S HOSPITAL · PI AUSTIN, S BRYN, ROSARIO, MARGARET · 2009 to 2013
$3.3M
Nurses Health Study 3: A multiple exposure environmental epidemiology cohort of young adultsR24ES028521 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI CHAVARRO, JORGE EDUARDO, LADEN, FRANCINE · 2018 to 2022
$2.1M
Policy- and Provider-Level Determinants of Human Papillomavirus Vaccination Disparities Among Young U.S. WomenK01CA234226 · NCI · TUFTS UNIVERSITY MEDFORD · PI AGÉNOR, MADINA · 2018 to 2020
$447k
NCI NIH HHS K01 CA234226NCI NIH HHS T32 CA009001NHLBI NIH HHS U01 HL145386NICHD NIH HHS R01 HD057368NICHD NIH HHS R01 HD066963NIEHS NIH HHS R24 ES028521
6 · The paper itself

Abstract

backgroundAlthough much has been published in recent years on differences in Papanicolaou (Pap) tests across sexual orientation, other aspects of cervical cancer prevention remain underexplored, such as human papillomavirus (HPV) vaccination, HPV co-tests, or abnormal Pap tests.

methodsData came from participants (aged 24-54 years) enrolled in an ongoing, longitudinal, U.S.-based cohort study, the Nurses' Health Study 3 (N = 12,175). Analyses were restricted to participants who met the current guidelines for care (e.g., ≥21 years of age for Pap tests).

resultsMostly heterosexual women were more likely to initiate HPV vaccination than completely heterosexual women with no same-sex partners. All other comparisons across sexual orientation for HPV vaccination initiation and completion and the age of initiation were not statistically significant. Compared with completely heterosexual women with no same-sex partners, mostly heterosexual and lesbian women had lower odds of having a Pap test within the past 2 years. Completely heterosexual women with same-sex partners, mostly heterosexual women, and bisexual women had their first Pap test at an earlier age, had higher odds of having an HPV co-test, and had higher odds of having a positive HPV or abnormal Pap test compared with completely heterosexual women with no same-sex partners. In contrast, lesbian women had lower odds of having positive HPV or abnormal Pap results (odds ratio, 0.65; 95% confidence interval, 0.49-0.86) than completely heterosexual women with no same-sex partners.

conclusionsThere are significant differences across sexual orientation groups in cervical cancer prevention for Pap test timing and positive HPV and abnormal Pap tests, but few differences in HPV vaccination initiation, completion, and age at initiation. Interventions should focus on increasing routine Pap testing among mostly heterosexual and lesbian women.

Indexed as

BisexualityHealth Knowledge, Attitudes, PracticeHeterosexualityHomosexuality, FemalePapillomavirus InfectionsUterine Cervical NeoplasmsVaccinationAdolescentAdultCohort StudiesFemaleHumansLongitudinal StudiesMiddle AgedOdds RatioPapanicolaou Test

Identifiers

PMID32249004
PMCPMC7347453

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.