Evidence map›Paper›PMID 32248918›Full record

ArticleIndian heart journal

Correlation of urinary cotinine with cardiovascular risk factors in pan masala tobacco users.

Sanjeeb Shrestha, Deebya Raj Mishra, Niraj Dhakal, Suresh Bhandari, Sagar Khanal, Madhab Lamsal

Open access · goldAbstract read
In one paragraph

Article in Indian heart journal. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Cardiovascular Risk Management in the South Asian Patient: A Review.Health sciences review (Oxford, England) · 2022
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sanjeeb ShresthaDepartment of Biochemistry, Gandaki Medical College and Teaching Hospital, Pokhara, Nepal. Electronic address: shresthasanjeeb11@gmail.com.
Deebya Raj MishraDepartment of Internal Medicine, B. P. Koirala Institute of Health Sciences, Dharan, Nepal. Electronic address: deebya.mishra@bpkihs.edu.
Niraj DhakalDepartment of Biochemistry, Gandaki Medical College and Teaching Hospital, Pokhara, Nepal. Electronic address: 2nirajdhakal@gmail.com.
Suresh BhandariDepartment of Biochemistry, Gandaki Medical College and Teaching Hospital, Pokhara, Nepal. Electronic address: princesureesh@hotmail.com.
Sagar KhanalDepartment of Biochemistry, Lumbini Medical College, Lumbini, Nepal. Electronic address: sagar20062@gmail.com.
Madhab LamsalDepartment of Biochemistry, B. P. Koirala Institute of Health Sciences, Dharan, Nepal. Electronic address: madhab.lamsal@bpkihs.edu.
Janaki Medical CollegeB.P. Koirala Institute of Health Sciences · NPLumbini Medical College

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTobacco consumption is considered as one of the major risk factors for cardiovascular (CV) morbidity. However, the effect of paan masala tobacco (PMT) (a type of smokeless tobacco) consumption has not been well studied in our context. Our study is aimed to find an association of CV risk factors between PMT users and nonusers and to correlate those parameters with urinary cotinine level, a degradation product of nicotine occurring in tobacco.

methodsThis comparative cross-sectional study was carried out among 200 participants. The effect of PMT use on CV risk factors such as blood pressure (BP), lipid profile, and body mass index was measured against urine cotinine level. Statistical tests used were χ

resultMean BP, total cholesterol, triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and median cotinine level were found to be significantly higher in PMT users than in controls (p < 0.001). Urinary cotinine level was positively correlated with mean BP, TC, TG, and LDL-C in PMT users (p < 0.001). Similarly, the odds of having hypercholesterolemia and increased diastolic BP was also significantly higher in PMT users (p < 0.001).

conclusionPMT use has an adverse effect on CV risk parameters and there is a rational of cotinine measurement for screening CV risk among PMT users.

Indexed as

Tobacco, SmokelessAdultCase-Control StudiesCholesterolCotinineCross-Sectional StudiesDiastoleFemaleHumansHypercholesterolemiaHypertensionLipoproteins, HDLLipoproteins, LDLMaleNepalRisk FactorsCholesterolCotinineLipoproteins, HDLLipoproteins, LDLTriglyceridesBlood pressureCardiovascularLipid-profilePan masala tobaccoUrinary cotinine

Identifiers

PMID32248918
PMCPMC7136352
OpenAlexW2981796059

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.