Evidence map›Paper›PMID 32248873›Full record

ArticleEpidemiology and psychiatric sciences2020

Associations between food insecurity and psychotropic medication use among women living with HIV in the United States.

Henry J Whittle, William R Wolfe, Lila A Sheira, Edward A Frongillo, Kartika Palar, Daniel Merenstein, Tracey E Wilson, Adebola Adedimeji, Mardge H Cohen, Eryka L Wentz and 2 more

Open access · goldAbstract read
In one paragraph

Article in Epidemiology and psychiatric sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 2 countries.

Henry J WhittleCentre for Psychiatry, Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, LondonEC1M 6BQ, UK.ORCID https://orcid.org/0000-0001-7685-860X
William R WolfeDepartment of Psychiatry, University of California, San Francisco (UCSF), San Francisco, CA, USA.
Lila A SheiraDivision of HIV, ID and Global Medicine, Department of Medicine, UCSF, San Francisco, CA, USA.
Edward A FrongilloDepartment of Health Promotion, Education, and Behavior, University of South Carolina, Columbia, SC, USA.
Kartika PalarDivision of HIV, ID and Global Medicine, Department of Medicine, UCSF, San Francisco, CA, USA.
Daniel MerensteinDepartment of Family Medicine, Georgetown University Medical Center, Washington, DC, USA.
Tracey E WilsonDepartment of Community Health Sciences, State University of New York Downstate Medical Center, School of Public Health, Brooklyn, NY, USA.
Adebola AdedimejiDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA.
Mardge H CohenDepartment of Medicine, Stroger Hospital, Chicago, IL, USA.
Eryka L WentzDepartment of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA.
Phyllis C TienDepartment of Medicine, UCSF and Medical Service, Department of Veteran Affairs Medical Center, San Francisco, CA, USA.
Sheri D WeiserDivision of HIV, ID and Global Medicine, Department of Medicine, UCSF, San Francisco, CA, USA.
Albert Einstein College of Medicine · USGeorgetown University · USJohn H. Stroger, Jr. Hospital of Cook County · USJohns Hopkins University · USQueen Mary University of London · GBSan Francisco AIDS Foundation · USSan Francisco VA Medical Center · USState University of New York · USUniversity of California, San Francisco · USUniversity of South Carolina · US

Funding

Ujima Mentoring ProgramP30MH062246 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Sheri Ann Lippman · 2001 to 2026
$57.4M
Sex differences in the role of multi-omics in HIV-associated carotid artery atherosclerosisU01HL146204 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI David B. Hanna, Anjali Sharma · 2019 to 2026
$33.2M
Pathways from Food Insecurity to Health and Treatment Outcomes in Women with HIVR01MH095683 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WEISER, SHERI DAWN · 2012 to 2016
$2.8M
Mentoring in Patient Oriented Research on Food Insecurity, HIV and AgingK24AI134326 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SHERI Dawn WEISER · 2017 to 2026
$1.4M
Acute Effects of Cannabis on Cognition and Mobility in Older HIV-Infected and Uninfected Women"R21AG059505 · NIA · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI SHARMA, ANJALI · 2018 to 2019
$318k
NHLBI NIH HHS U01 HL146204NIAID NIH HHS K24 AI134326NIA NIH HHS R21 AG059505NIMH NIH HHS P30 MH062246NIMH NIH HHS R01 MH095683
6 · The paper itself

Abstract

aimsPsychotropic prescription rates continue to increase in the United States (USA). Few studies have investigated whether social-structural factors may play a role in psychotropic medication use independent of mental illness. Food insecurity is prevalent among people living with HIV in the USA and has been associated with poor mental health. We investigated whether food insecurity was associated with psychotropic medication use independent of the symptoms of depression and anxiety among women living with HIV in the USA.

methodsWe used cross-sectional data from the Women's Interagency HIV Study (WIHS), a nationwide cohort study. Food security (FS) was the primary explanatory variable, measured using the Household Food Security Survey Module. First, we used multivariable linear regressions to test whether FS was associated with symptoms of depression (Center for Epidemiologic Studies Depression [CESD] score), generalised anxiety disorder (GAD-7 score) and mental health-related quality of life (MOS-HIV Mental Health Summary score; MHS). Next, we examined associations of FS with the use of any psychotropic medications, including antidepressants, sedatives and antipsychotics, using multivariable logistic regressions adjusting for age, race/ethnicity, income, education and alcohol and substance use. In separate models, we additionally adjusted for symptoms of depression (CESD score) and anxiety (GAD-7 score).

resultsOf the 905 women in the sample, two-thirds were African-American. Lower FS (i.e. worse food insecurity) was associated with greater symptoms of depression and anxiety in a dose-response relationship. For the psychotropic medication outcomes, marginal and low FS were associated with 2.06 (p < 0.001; 95% confidence interval [CI] = 1.36-3.13) and 1.99 (p < 0.01; 95% CI = 1.26-3.15) times higher odds of any psychotropic medication use, respectively, before adjusting for depression and anxiety. The association of very low FS with any psychotropic medication use was not statistically significant. A similar pattern was found for antidepressant and sedative use. After additionally adjusting for CESD and GAD-7 scores, marginal FS remained associated with 1.93 (p < 0.05; 95% CI = 1.16-3.19) times higher odds of any psychotropic medication use. Very low FS, conversely, was significantly associated with lower odds of antidepressant use (adjusted odds ratio = 0.42; p < 0.05; 95% CI = 0.19-0.96).

conclusionsMarginal FS was associated with higher odds of using psychotropic medications independent of depression and anxiety, while very low FS was associated with lower odds. These complex findings may indicate that people experiencing very low FS face barriers to accessing mental health services, while those experiencing marginal FS who do access services are more likely to be prescribed psychotropic medications for distress arising from social and structural factors.

Indexed as

Quality of LifeAdultAntidepressive AgentsAntipsychotic AgentsAnxietyCohort StudiesCross-Sectional StudiesDepressionFemaleFood SupplyHIV InfectionsHumansHypnotics and SedativesMental DisordersMental HealthPovertyAntidepressive AgentsAntipsychotic AgentsHypnotics and SedativesPsychotropic DrugsAIDSpsychiatric servicespsychotropic drugssocial and political issueswomen

Identifiers

PMID32248873
PMCPMC7214522
OpenAlexW3014140782

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.