ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2020
Potential factors influencing replay across CA1 during sharp-wave ripples.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 34 citations in OpenAlex.
- Article
- Article
- Differential vulnerability of CA1 pyramidal neuron cell types in the 5xFAD Alzheimer's disease mouse model.bioRxiv : the preprint server for biology · 2026Article
- Laminar organization of pyramidal neuron cell types defines distinct CA1 hippocampal subregions.Nature communications · 2025Article
- REM sleep prefrontal ripple chains mediate distinct cortical-hippocampal reactivation patterns compared to NREM ripples.bioRxiv : the preprint server for biology · 2025Article
- Differential contributions of CA3 and entorhinal cortex inputs to ripple patterns in the hippocampus.iScience · 2025Article
- Prefrontal cortical ripples mediate top-down suppression of hippocampal reactivation during sleep memory consolidation.Current biology : CB · 2024Article
- A machine learning toolbox for the analysis of sharp-wave ripples reveals common waveform features across species.Communications biology · 2024Article
- Cortical ripples mediate top-down suppression of hippocampal reactivation during sleep memory consolidation.bioRxiv : the preprint server for biology · 2023Article
- Topological analysis of sharp-wave ripple waveforms reveals input mechanisms behind feature variations.Nature neuroscience · 2023Article
- Theta-band phase locking during encoding leads to coordinated entorhinal-hippocampal replay.Current biology : CB · 2023Article
- Hippocampal memory reactivation during sleep is correlated with specific cortical states of the retrosplenial and prefrontal cortices.Learning & memory (Cold Spring Harbor, N.Y.) · 2023Article
- Disrupting ripples: Methods, results, and caveats in closed-loop approaches in rodents.Journal of sleep research · 2022Review
- Replay, the default mode network and the cascaded memory systems model.Nature reviews. Neuroscience · 2022Review
- Article
- Inhibition allocates spikes during hippocampal ripples.Nature communications · 2022Article
- Generalized Simultaneous Localization and Mapping (G-SLAM) as unification framework for natural and artificial intelligences: towards reverse engineering the hippocampal/entorhinal system and principles of high-level cognition.Frontiers in systems neuroscience · 2022Article
- An update to Hippocampome.org by integrating single-cell phenotypes with circuit function in vivo.PLoS biology · 2021Article
- Sharp Wave Ripples in Alzheimer's Disease: In Search of Mechanisms.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Memories replayed: reactivating past successes and new dilemmas.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sharp-wave ripples are complex neurophysiological events recorded along the trisynaptic hippocampal circuit (i.e. from CA3 to CA1 and the subiculum) during slow-wave sleep and awake states. They arise locally but scale brain-wide to the hippocampal target regions at cortical and subcortical structures. During these events, neuronal firing sequences are replayed retrospectively or prospectively and in the forward or reverse order as defined by experience. They could reflect either pre-configured firing sequences, learned sequences or an option space to inform subsequent decisions. How can different sequences arise during sharp-wave ripples? Emerging data suggest the hippocampal circuit is organized in different loops across the proximal (close to dentate gyrus) and distal (close to entorhinal cortex) axis. These data also disclose a so-far neglected laminar organization of the hippocampal output during sharp-wave events. Here, I discuss whether by incorporating cell-type-specific mechanisms converging on deep and superficial CA1 sublayers along the proximodistal axis, some novel factors influencing the organization of hippocampal sequences could be unveiled. This article is part of the Theo Murphy meeting issue 'Memory reactivation: replaying events past, present and future'.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.