ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2020
Neural ensemble reactivation in rapid eye movement and slow-wave sleep coordinate with muscle activity to promote rapid motor skill learning.
Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 35 citations in OpenAlex.
- Motor cortex activity during sleep and wake movements sharpens across development but continues to lag the red nucleus.Scientific reports · 2026Article
- Rocking-induced sleep enhancement promotes motor learning through transcriptional and synaptic remodelling.Communications biology · 2026Article
- Systems memory consolidation during sleep: oscillations, neuromodulators, and synaptic remodeling.BMB reports · 2025Review
- Article
- Cortical reactivation of spatial and non-spatial features coordinates with hippocampus to form a memory dialogue.Nature communications · 2023Article
- Neural decoding reveals specialized kinematic tuning after an abrupt cortical transition.Cell reports · 2023Article
- Reciprocal relationships between sleep and smell.Frontiers in neural circuits · 2022Review
- Replay in Deep Learning: Current Approaches and Missing Biological Elements.Neural computation · 2021Article
- Replay of innate vocal patterns during night sleep in suboscines.Proceedings. Biological sciences · 2021Article
- Motor imagery practice benefits during arm immobilization.Scientific reports · 2021Article
- Reliable induction of sleep spindles with intracranial electrical pulse stimulation.Learning & memory (Cold Spring Harbor, N.Y.) · 2021Article
- Memories replayed: reactivating past successes and new dilemmas.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2020Article
- Assessment of Sleep, K-Complexes, and Sleep Spindles in a T21 Light-Dark Cycle.Frontiers in neuroscience · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 2 countries.
Funding
Abstract
Neural activity patterns of recent experiences are reactivated during sleep in structures critical for memory storage, including hippocampus and neocortex. This reactivation process is thought to aid memory consolidation. Although synaptic rearrangement dynamics following learning involve an interplay between slow-wave sleep (SWS) and rapid eye movement (REM) sleep, most physiological evidence implicates SWS directly following experience as a preferred window for reactivation. Here, we show that reactivation occurs in both REM and SWS and that coordination of REM and SWS activation on the same day is associated with rapid learning of a motor skill. We performed 6 h recordings from cells in rats' motor cortex as they were trained daily on a skilled reaching task. In addition to SWS following training, reactivation occurred in REM, primarily during the pre-task rest period, and REM and SWS reactivation occurred on the same day in rats that acquired the skill rapidly. Both pre-task REM and post-task SWS activation were coordinated with muscle activity during sleep, suggesting a functional role for reactivation in skill learning. Our results provide the first demonstration that reactivation in REM sleep occurs during motor skill learning and that coordinated reactivation in both sleep states on the same day, although at different times, is beneficial for skill learning. This article is part of the Theo Murphy meeting issue 'Memory reactivation: replaying events past, present and future'.
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Registered trials
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