ArticleCritical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine2020
Critically ill patients with COVID-19 in Hong Kong: a multicentre retrospective observational cohort study
Article in Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 10 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
42 citing papers in PubMed, 10 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Efficacy and safety of hyperbaric oxygen treatment to treat COVID-19 pneumonia: a living systematic review update.Diving and hyperbaric medicine · 2022Pooled it
- Asthma and risk of infection, hospitalization, ICU admission and mortality from COVID-19: Systematic review and meta-analysis.The Journal of asthma : official journal of the Association for the Care of Asthma · 2022Pooled it
- Incidence and Outcomes of Acute Kidney Injury in COVID-19: A Systematic Review.Blood purification · 2022Pooled it
- Epidemiological and clinical characteristics of non-severe and severe pediatric and adult COVID-19 patients across different geographical regions in the early phase of pandemic: a systematic review and meta-analysis of observational studies.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2021Pooled it
- Efficacy and safety of hyperbaric oxygen treatment in SARS-COV-2 (COVID-19) pneumonia: a systematic review.Diving and hyperbaric medicine · 2021Pooled it
- Central nervous system manifestations in COVID-19 patients: A systematic review and meta-analysis.Brain and behavior · 2021Pooled it
- Mortality in patients admitted to intensive care with COVID-19: an updated systematic review and meta-analysis of observational studies.Anaesthesia · 2021Pooled it
- Pooled it
- Bacterial co-infection and secondary infection in patients with COVID-19: a living rapid review and meta-analysis.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2020Pooled it
- Rate of Intensive Care Unit admission and outcomes among patients with coronavirus: A systematic review and Meta-analysis.PloS one · 2020Pooled it
- Survival Analysis of Hospital Length of Stay of COVID-19 Patients in Ilam Province, Iran: A Retrospective Cross-Sectional Study.Journal of clinical medicine · 2023Article
- Simulation of New York City's Ventilator Allocation Guideline During the Spring 2020 COVID-19 Surge.JAMA network open · 2023Article
- Article
- A comparative study of mortality differences and associated characteristics among elderly and young adult patients hospitalised with COVID-19 in India.BMC geriatrics · 2023Article
- How Common SOFA and Ventilator Time Trial Criteria Would Have Performed During the COVID-19 Pandemic: An Observational Simulated Cohort Study.Disaster medicine and public health preparedness · 2022Observational
- Fungal and bacterial co-infections of the respiratory tract among patients with COVID-19 hospitalized in intensive care units.Gene reports · 2022Article
- Potential mechanisms underlying lithium treatment for Alzheimer's disease and COVID-19.European review for medical and pharmacological sciences · 2022Review
- Bacterial infections in critically ill patients with SARS-2-COVID-19 infection: results of a prospective observational multicenter study.Infection · 2022Observational
- The Collateral Effects of COVID-19 Pandemic on the Status of Carbapenemase-Producing Pathogens.Frontiers in cellular and infection microbiology · 2022Review
- ISARIC-4C Mortality Score overestimates risk of death due to COVID-19 in Australian ICU patients: a validation cohort study.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2021Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To report the first eight cases of critically ill patients with coronavirus disease 2019 (COVID-19) in Hong Kong, describing the treatments and supportive care they received and their 28-day outcomes. Design: Multicentre retrospective observational cohort study. Setting: Three multidisciplinary intensive care units (ICUs) in Hong Kong. Participants: All adult critically ill patients with confirmed COVID-19 admitted to ICUs in Hong Kong between 22 January and 11 February 2020. Main outcome measure: 28-day mortality. Results: Eight out of 49 patients with COVID-19 (16%) were admitted to Hong Kong ICUs during the study period. The median age was 64.5 years (range, 42–70) with a median admission Sequential Organ Failure Assessment (SOFA) score of 6 (IQR, 4–7). Six patients (75%) required mechanical ventilation, six patients (75%) required vasopressors and two (25%) required renal replacement therapy. None of the patients required prone ventilation, nitric oxide or extracorporeal membrane oxygenation. The median times to shock reversal and extubation were 9 and 11 days respectively. At 28 days, one patient (12%) had died and the remaining seven (88%) all survived to ICU discharge. Only one of the survivors (14%) still required oxygen at 28 days. Conclusion: Critically ill patients with COVID-19 often require a moderate duration of mechanical ventilation and vasopressor support. Most of these patients recover and survive to ICU discharge with supportive care using lung protective ventilation strategies, avoiding excess fluids, screening and treating bacterial co-infection, and timely intubation. Lower rather than upper respiratory tract viral burden correlates with clinical severity of illness.
Identifiers
32248675PMC10692444W3015053717What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.