Evidence map›Paper›PMID 32248644›Full record

ArticleGenes, brain, and behavior2020

Phenotypic profiling of mGlu

Nicole M Fisher, Robert W Gould, Rocco G Gogliotti, Annalise J McDonald, Hana Badivuku, Susmita Chennareddy, Aditi B Buch, Annah M Moore, Matthew T Jenkins, W Hudson Robb and 4 more

Open access · greenAbstract read
In one paragraph

Article in Genes, brain, and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 33 citations in OpenAlex.

  1. Molecular pharmacology of mGluMolecular pharmacology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Overexpression of mGluMolecular neurobiology · 2025
    Article
  6. Profiling the Impact of mGluACS chemical neuroscience · 2025
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. GRM7 gene mutations and consequences for neurodevelopment.Pharmacology, biochemistry, and behavior · 2023
    Review
  14. MACS chemical neuroscience · 2023
    Article
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Nicole M FisherDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.ORCID 0000-0001-6740-9618
Robert W GouldDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.
Rocco G GogliottiDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.
Annalise J McDonaldDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.
Hana BadivukuDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.
Susmita ChennareddyDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.
Aditi B BuchDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.
Annah M MooreDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.
Matthew T JenkinsDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.
W Hudson RobbDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.
Craig W LindsleyDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.
Carrie K JonesDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.
P Jeffrey ConnDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.
Colleen M NiswenderDepartment of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA.
Vanderbilt University · US

Funding

TRAINING IN PHARMACOLOGICAL SCIENCEST32GM007628 · NIGMS · VANDERBILT UNIVERSITY · PI BARNETT, JOEY VICTOR, KAVALALI, EGE T · 1985 to 2022
$11.2M
Research Project: Sensory and Multisensory Contributions to AutismU54HD083211 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DYKENS, ELISABETH MAY · 2015 to 2019
$7.1M
Molecular and Behavioral Neurobiology of Transcription Factor TCF4R01MH104158 · NIMH · VANDERBILT UNIVERSITY · PI NISWENDER, COLLEEN M · 2014 to 2018
$1.9M
A precision medicine approach to Rett SyndromeR01NS112171 · NINDS · LOYOLA UNIVERSITY CHICAGO · PI GOGLIOTTI, ROCCO GEORGE · 2020 to 2024
$1.7M
Development of a Selective Metabotropic Glutamate Receptor 7 Allosteric Modulator ProbeR01MH113543 · NIMH · VANDERBILT UNIVERSITY · PI LINDSLEY, CRAIG, NISWENDER, COLLEEN M · 2017 to 2019
$1.2M
Partial mGlu5 Negative Allosteric Modulators to Prevent Relapse to Cocaine AbuseR00DA042129 · NIDA · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI GOULD, ROBERT WARREN · 2019 to 2021
$747k
Normalizing E:I imbalance in Rett Syndrome by Modulation of Late Response GenesK01MH112983 · NIMH · VANDERBILT UNIVERSITY · PI GOGLIOTTI, ROCCO GEORGE · 2017 to 2020
$543k
Partial mGlu5 Negative Allosteric Modulators to Prevent Relapse to Cocaine AbuseK99DA042129 · NIDA · VANDERBILT UNIVERSITY · PI GOULD, ROBERT WARREN · 2017 to 2018
$183k
Metabotropic Glutamate Receptor 7 as a Novel Therapeutic Target for MECP2 Duplication SyndromeF31MH113259 · NIMH · VANDERBILT UNIVERSITY · PI FISHER, NICOLE MARIE · 2017 to 2019
$88k
NICHD NIH HHS U54 HD083211NIDA NIH HHS DA042129NIDA NIH HHS K99 DA042129NIDA NIH HHS R00 DA042129NIGMS NIH HHS T32 GM007628NIMH NIH HHS F31 MH113259NIMH NIH HHS K01 MH112983NIMH NIH HHS R01 MH104158NIMH NIH HHS R01 MH113543NINDS NIH HHS R01 NS112171
6 · The paper itself

Abstract

Neurodevelopmental disorders are characterized by deficits in communication, cognition, attention, social behavior and/or motor control. Previous studies have pointed to the involvement of genes that regulate synaptic structure and function in the pathogenesis of these disorders. One such gene, GRM7, encodes the metabotropic glutamate receptor 7 (mGlu

Indexed as

Amphetamine-Related DisordersAnimalsEpilepsyFemaleLearningMaleMiceNeurodevelopmental DisordersPhenotypeReceptors, Metabotropic GlutamateSleepSocial Behaviormetabotropic glutamate receptor 7Receptors, Metabotropic GlutamateADHDASDautismEEGepilepsyGRM7mGlu7Rett syndromeseizures

Identifiers

PMID32248644
PMCPMC8034495
OpenAlexW3015024282

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.