Evidence map›Paper›PMID 32248405›Full record

ArticleFolia microbiologica2020

Concentration of NK cells after β-glucan and vitamin D supplementation in patients with diabetic retinopathy.

Richter Josef, Pohorska Jitka, Závorková Martina, Král Vlastimil, Stiborova Ivana, Dobiasova Rajnohova Lucie, Vetvicka Vaclav

Abstract read
PubMed Publisher
In one paragraph

Article in Folia microbiologica, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Diabetic macular edema treatment with subthreshold micropulse laser - five-year long monitoring.Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia · 2023
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Richter JosefZdravotní ústav se sídlem v Ústí nad Labem, Usti nad Labem, Czech Republic.
Pohorska JitkaZdravotní ústav se sídlem v Ústí nad Labem, Usti nad Labem, Czech Republic.
Závorková MartinaOční klinika UJEP Masarykova nemocnice, Krajská zdravotní, a.s., Usti nad Labem, Czech Republic.
Král VlastimilZdravotní ústav se sídlem v Ústí nad Labem, Usti nad Labem, Czech Republic.
Stiborova IvanaZdravotní ústav se sídlem v Ústí nad Labem, Usti nad Labem, Czech Republic.
Dobiasova Rajnohova LucieZdravotní ústav se sídlem v Ústí nad Labem, Usti nad Labem, Czech Republic.
Vetvicka VaclavDepartment of Pathology, University of Louisville, 511 S. Floyd St., Louisville, KY, 40202, USA. Vaclav.vetvicka@louisville.edu.
Zdravotní Ústav Se Sídlem v Ústí nad Labem · CZOcní klinika · CZUniversity of Louisville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In our study, we focused on possible effects of supplementation with glucan and vitamin D on total numbers of NK cells in patients with diabetic retinopathy. We evaluated possible relations among nutritional state (BMI), leptin levels, and total numbers of NK cells in patients supplemented with (1) glucan and vitamin D, (2) vitamin D and placebo, and (3) vitamin D alone. Our results show that 3 months of supplementation with both glucan and vitamin D resulted in significant improvements of NK cell numbers. In addition, we found statistically significant correlation between NK cell numbers and leptin levels. Based on these results, we propose that the molecule responsible for these changes is glucan, as vitamin D alone or together with placebo caused no effects.

Indexed as

Dietary SupplementsAgedbeta-GlucansDiabetes Mellitus, Type 2Diabetic RetinopathyFemaleHumansImmunomodulationKiller Cells, NaturalLeptinLymphocyte CountMaleMiddle AgedVitamin Dbeta-GlucansLeptinVitamin D

Identifiers

PMID32248405
OpenAlexW3015165509

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.