Evidence map›Paper›PMID 32248365›Full record

ArticleEuropean radiology2020

Baseline

Nicolas Aide, Christophe Fruchart, Catherine Nganoa, Anne-Claire Gac, Charline Lasnon

Abstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 2 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 92 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. A proof of concept study ofScientific reports · 2025
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  7. Radiomics based onQuantitative imaging in medicine and surgery · 2025
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  8. Review
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  12. Review
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  15. Article
  16. Review
  17. Article
  18. Semiquantitative 2-[Frontiers in medicine · 2024
    Review
  19. Article
  20. BaselineEJNMMI research · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Nicolas AideNuclear Medicine Department, Caen University Hospital, Caen, France.
Christophe FruchartHaematology Institute, François Baclesse Cancer Centre, Caen, France.
Catherine NganoaNuclear Medicine Department, Caen University Hospital, Caen, France.
Anne-Claire GacHaematology Institute, Caen University Hospital, Caen, France.
Charline LasnonINSERM 1086 ANTICIPE, Normandie University, Caen, France. c.lasnon@baclesse.unicancer.fr.ORCID https://orcid.org/0000-0001-5643-1668
Inserm · FRUniversité de Caen Normandie · FRCentre François Baclesse · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the prognostic value of positron emission tomography (PET) radiomic features in the field of diffuse large B cell lymphoma (DLBCL) treated with a first-line immunochemotherapy.

methodsOne-hundred thirty-two patients newly diagnosed with DLBCL were retrospectively included. PET studies were reconstructed using an ordered subset expectation maximisation algorithm with point spread function modelling. The total metabolic tumour volume (MTV) was recorded for each patient, and the volume of interest structure of the largest target lesion was used to compute

resultsThe median follow-up was 27 months, and the 2-year event-free survival (2y-EFS) was 77.3% in the entire population. ROC analyses for the 2y-EFS reached statistical significance for total MTV as well as four second-order metrics (homogeneity, contrast, correlation, dissimilarity) and five third-order metrics (LZE (Long-Zone Emphasis), LZLGE (Long-Zone Low-Grey Level Emphasis), LZHGE (Long-Zone High-Grey Level Emphasis), GLNU (Grey-Level Non-Uniformity) and ZP (Zone Percentage)). LZHGE displayed the highest ROC analysis accuracy (acc. = 0.76) and the best discriminant value on univariable Kaplan-Meier analysis (p < 0.0001, HR = 4.54). On multivariable analysis, including IPIaa, total MTV and LZHGE, LZHGE was the only independent predictor of 2y-EFS. These results were confirmed on the validation dataset.

conclusionsBaseline KEY POINTS: •

Indexed as

AdultAgedAged, 80 and overAntineoplastic AgentsFemaleFluorodeoxyglucose F18HumansImmunotherapyLymphoma, Large B-Cell, DiffuseMaleMiddle AgedPositron Emission Tomography Computed TomographyPrognosisProgression-Free SurvivalRadiopharmaceuticalsRetrospective StudiesAntineoplastic AgentsFluorodeoxyglucose F18RadiopharmaceuticalsFluorodeoxyglucose F18Image processing, computer-assistedLymphoma, large B cell, diffusePositron emission tomography computed tomography

Identifiers

PMID32248365
OpenAlexW3014286814

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.