Evidence map›Paper›PMID 32248315›Full record

ArticleBulletin of mathematical biology2020

Adaptive Bet-Hedging Revisited: Considerations of Risk and Time Horizon.

Omri Tal, Tat Dat Tran

Abstract read
In one paragraph

Article in Bulletin of mathematical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Omri TalMax Planck Institute for Mathematics in the Sciences, Inselstrasse 22, 04103, Leipzig, Germany. omrit1248@gmail.com.ORCID http://orcid.org/0000-0002-6370-6786
Tat Dat TranMax Planck Institute for Mathematics in the Sciences, Inselstrasse 22, 04103, Leipzig, Germany.ORCID http://orcid.org/0000-0001-5299-7023

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Models of adaptive bet-hedging commonly adopt insights from Kelly's famous work on optimal gambling strategies and the financial value of information. In particular, such models seek evolutionary solutions that maximize long-term average growth rate of lineages, even in the face of highly stochastic growth trajectories. Here, we argue for extensive departures from the standard approach to better account for evolutionary contingencies. Crucially, we incorporate considerations of volatility minimization, motivated by interim extinction risk in finite populations, within a finite time horizon approach to growth maximization. We find that a game-theoretic competitive optimality approach best captures these additional constraints and derive the equilibria solutions under straightforward fitness payoff functions and extinction risks. We show that for both maximal growth and minimal time relative payoffs, the log-optimal strategy is a unique pure strategy symmetric equilibrium, invariant with evolutionary time horizon and robust to low extinction risks.

Indexed as

GamblingGame TheoryModels, TheoreticalAdaptation, PhysiologicalBiological EvolutionExtinction, BiologicalGenetic Association StudiesGenetic FitnessGenetics, PopulationGerminationHumansMathematical ConceptsModels, BiologicalPlant Physiological PhenomenaPlantsRisk FactorsAdaptive bet-hedgingExtinction riskFinite time horizonGame theoryGrowth-optimal portfolio theoryKelly gambling

Identifiers

PMID32248315
PMCPMC7128013

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.