Evidence map›Paper›PMID 32248310›Full record

ArticleBulletin of mathematical biology2020

Circular Tessera Codes in the Evolution of the Genetic Code.

Elena Fimmel, Martin Starman, Lutz Strüngmann

Abstract read
In one paragraph

Article in Bulletin of mathematical biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Equivalence classes of circular codes induced by permutation groups.Theory in biosciences = Theorie in den Biowissenschaften · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Elena FimmelInstitute of Mathematical Biology, Faculty for Computer Sciences, Mannheim University of Applied Sciences, 68163, Mannheim, Germany. e.fimmel@hs-mannheim.de.
Martin StarmanInstitute of Mathematical Biology, Faculty for Computer Sciences, Mannheim University of Applied Sciences, 68163, Mannheim, Germany.
Lutz StrüngmannInstitute of Mathematical Biology, Faculty for Computer Sciences, Mannheim University of Applied Sciences, 68163, Mannheim, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The origin of the modern genetic code and the mechanisms that have contributed to its present form raise many questions. The main goal of this work is to test two hypotheses concerning the development of the genetic code for their compatibility and complementarity and see if they could benefit from each other. On the one hand, Gonzalez, Giannerini and Rosa developed a theory, based on four-based codons, which they called tesserae. This theory can explain the degeneracy of the modern vertebrate mitochondrial code. On the other hand, in the 1990s, so-called circular codes were discovered in nature, which seem to ensure the maintenance of a correct reading-frame during the translation process. It turns out that the two concepts not only do not contradict each other, but on the contrary complement and enrichen each other.

Indexed as

Evolution, MolecularGenetic CodeModels, GeneticAnimalsCodonGenes, MitochondrialHumansMathematical ConceptsProtein BiosynthesisReading FramesVertebratesCodonCircular codeDegeneracyGenetic codeTessera

Identifiers

PMID32248310
PMCPMC7128014

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.