Evidence map›Paper›PMID 32247933›Full record

ArticleGeneral hospital psychiatry

Association between DSM-5 and ICD-11 personality dimensional traits in a general medical cohort and readmission and mortality.

Sergio A Barroilhet, Alexandra E Bieling, Thomas H McCoy, Roy H Perlis

Open access · bronzeAbstract read
In one paragraph

Article in General hospital psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Sergio A BarroilhetCenter for Quantitative Health, Division of Clinical Research and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Harvard University, Boston, MA, USA; University Psychiatric Clinic, University of Chile Clinical Hospital, Santiago, Chile.
Alexandra E BielingCenter for Quantitative Health, Division of Clinical Research and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Thomas H McCoyCenter for Quantitative Health, Division of Clinical Research and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Harvard University, Boston, MA, USA.
Roy H PerlisCenter for Quantitative Health, Division of Clinical Research and Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Harvard University, Boston, MA, USA. Electronic address: rperlis@partners.org.
Massachusetts General Hospital · USHarvard University · USUniversity of Chile · CL

Funding

Natural language processing for characterizing psychopathologyR01MH106577 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI PERLIS, ROY H. · 2016 to 2018
$1.2M
NIMH NIH HHS R01 MH106577
6 · The paper itself

Abstract

backgroundPersonality has long been studied as a factor associated with health outcomes. Investigations of large, generalizable clinical cohorts are limited by variations in personality diagnostic methodologies and difficulties with long-term follow-up.

methodsElectronic health records of a cohort of patients admitted to a general hospital were characterized using a previously developed natural language processing tool for extracting DSM-5 and ICD-11 personality domains. We used Cox regression and Fine-Gray competing risk survival to analyze the relationships between these personality estimates, sociodemographic features, and risk of readmission and mortality.

resultsAmong 12,274 patients, 2379 deaths occurred in the course of 61,761 patient-years at risk, with 19,985 admissions during follow-up. Detachment was the most common personality feature. Presence of disinhibition was independently associated with a higher mortality risk, while anankastic traits were associated with a lower mortality risk. Increased likelihood of readmission was predicted by detachment, while decreased likelihood of readmission was associated with disinhibition and psychoticism traits.

conclusionsPersonality features can be identified from electronic health records and are associated with readmission and mortality risk. Developing treatment strategies that target patients with higher personality symptom burden in specific dimensions could enable more efficient and focused interventions.

Indexed as

AdultAgedAged, 80 and overCohort StudiesComorbidityDiagnostic and Statistical Manual of Mental DisordersElectronic Health RecordsFemaleHumansInternational Classification of DiseasesMachine LearningMaleMiddle AgedNatural Language ProcessingNoncommunicable DiseasesPatient ReadmissionElectronic health recordMachine learningMortalityNatural language processingPersonality disorderPersonality domainsReadmission

Identifiers

PMID32247933
PMCPMC9945433
OpenAlexW3003547090

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.