Evidence map›Paper›PMID 32247775›Full record

ArticleAmerican journal of ophthalmology2020

The Effect of Axial Length on Extraocular Muscle Leverage.

Robert A Clark, Joseph L Demer

Abstract read
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Article in American journal of ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Robert A ClarkDepartment of Ophthalmology, Interdepartmental Programs, David Geffen Medical School, University of California, Los Angeles, Los Angeles, California, USA.
Joseph L DemerDepartment of Ophthalmology, Interdepartmental Programs, David Geffen Medical School, University of California, Los Angeles, Los Angeles, California, USA; Department of Neurology, Interdepartmental Programs, David Geffen Medical School, University of California, Los Angeles, Los Angeles, California, USA; Department of Neuroscience, Interdepartmental Programs, David Geffen Medical School, University of California, Los Angeles, Los Angeles, California, USA; Department of Biomedical Engineering, Interdepartmental Programs, David Geffen Medical School, University of California, Los Angeles, Los Angeles, California, USA. Electronic address: jld@jsei.ucla.edu.

Funding

Vision Research Core at UCLAP30EY000331 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Xian-Jie Yang · 1985 to 2026
$16.8M
BIOMECHANICAL ANALYSIS IN STRABISMUS SURGERYR01EY008313 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JOSEPH Louis DEMER · 1991 to 2026
$15.0M
NEI NIH HHS P30 EY000331NEI NIH HHS R01 EY008313
6 · The paper itself

Abstract

purposeMagnetic resonance imaging was used to determine the effect of axial length (AL) on globe rotational axis and horizontal extraocular muscle leverage during horizontal duction.

designProspective observational case series.

methodsAt a single academic center, 36 orthophoric adults with a wide range of ALs underwent high-resolution axial orbital magnetic resonance imaging in target-controlled adduction and abduction. ALs were measured in planes containing maximum globe cross-sections. Area centroids were calculated to determine globe centers. Rotational axes in orbital coordinates were calculated from displacements of lens centers and globe-optic nerve attachments. Lever arms were calculated as distances between published extraocular muscle insertions and rotational axes.

resultsALs averaged 26.3 ± 0.3 mm (standard error [range 21.5-33.4 mm]). Rotational axes from adduction to abduction averaged 1.1 ± 0.2 mm medial and 1.1 ± 0.2 mm anterior to the globe's geometric center in adduction. Linear regression demonstrated no significant correlation between AL and rotational axis horizontal (R

conclusionsRegardless of AL, the globe rotates about a point nasal and anterior to its geometric center, giving the LR more leverage than the MR. This eccentricity may diminish the effect of tendon repositioning in moderate to highly myopic patients, with reductions in per-mill imeter dose/response predicted with longer AL.

Indexed as

AdultAgedAxial Length, EyeEye MovementsFemaleHealthy VolunteersHumansMagnetic Resonance ImagingMaleMiddle AgedOculomotor MusclesProspective StudiesTendons

Identifiers

PMID32247775
PMCPMC7434654

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.