Evidence map›Paper›PMID 32246920›Full record

ArticleThe American journal of pathology2020

Atrophy and Death of Nonpeptidergic and Peptidergic Nociceptive Neurons in SIV Infection.

Jake A Robinson, Guy Guenthner, Rebecca Warfield, Jessica R Kublin, Mandy D Smith, Masoud Shekarabi, Andrew D Miller, Tricia H Burdo

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Jake A RobinsonDepartment of Neuroscience, Temple University, Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
Guy GuenthnerDepartment of Biology, Boston College, Chestnut Hill, Massachusetts.
Rebecca WarfieldDepartment of Neuroscience, Temple University, Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
Jessica R KublinDepartment of Biology, Boston College, Chestnut Hill, Massachusetts.
Mandy D SmithDepartment of Neuroscience, Temple University, Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
Masoud ShekarabiDepartment of Neuroscience, Temple University, Lewis Katz School of Medicine, Philadelphia, Pennsylvania.
Andrew D MillerSection of Anatomic Pathology, Department of Biomedical Sciences, Cornell University College of Veterinary Medicine, Ithaca, New York.
Tricia H BurdoDepartment of Neuroscience, Temple University, Lewis Katz School of Medicine, Philadelphia, Pennsylvania. Electronic address: burdot@temple.edu.
Temple University · USBoston College · USCornell University · US

Funding

Tulane NPRC SPF Sheltered Outdoor Enclosure ExpansionP51OD011104 · OD · TULANE UNIVERSITY OF LOUISIANA · PI L Lee HAMM · 2012 to 2026
$142.4M
Viral Gene Editing and Bioinformatics Core for Institution # 269291P30MH092177 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI Ilker Kudret Sariyer · 2011 to 2026
$24.9M
RESOURCE FOR NONHUMAN PRIMATE CELL DEPLETING ANTIBODIESR24RR016001 · NCRR · BETH ISRAEL DEACONESS MEDICAL CENTER · PI REIMANN, KEITH A. · 2000 to 2011
$8.1M
Interdisciplinary And Translational Research Training In NeurohivT32MH079785 · NIMH · TEMPLE UNIV OF THE COMMONWEALTH · PI Kamel Khalili · 2008 to 2026
$5.4M
HIGH RESOLUTION STRUCTURAL STUDY OF DSDNA BACTERIOPHAGER01AI040101 · NIAID · SCRIPPS RESEARCH INSTITUTE, THE · PI JOHNSON, JOHN EMIL · 1996 to 2014
$5.2M
Monocyte/macrophage traffic and peripheral nerve pathogenesisR01NS082116 · NINDS · TEMPLE UNIV OF THE COMMONWEALTH · PI BURDO, TRICIA HELEN · 2012 to 2016
$2.0M
NCRR NIH HHS R24 RR016001NIAID NIH HHS R01 AI040101NIH HHS P51 OD011104NIMH NIH HHS P30 MH092177NIMH NIH HHS T32 MH079785NINDS NIH HHS R01 NS082116
6 · The paper itself

Abstract

HIV-associated sensory neuropathy is a common neurologic comorbidity of HIV infection and prevails in the post-antiretroviral therapy (ART) era. HIV infection drives pathologic changes in the dorsal root ganglia (DRG) through inflammation, altered metabolism, and neuronal dysfunction. Herein, we characterized specific neuronal populations in an SIV-infected macaque model with or without ART. DRG neuronal populations were identified by neurofilament H-chain 200, I-B

Indexed as

AnimalsAnti-Retroviral AgentsAtrophyGanglia, SpinalLectinsMacaca mulattaMaleNociceptorsPolyneuropathiesReceptor, trkASimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusAnti-Retroviral AgentsLectinsReceptor, trkA

Identifiers

PMID32246920
PMCPMC7322364
OpenAlexW3014180643

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.