Evidence map›Paper›PMID 32246841›Full record

ArticleAllergy2020

Epinephrine drives human M2a allergic macrophages to a regulatory phenotype reducing mast cell degranulation in vitro.

Jelena Gotovina, Rodolfo Bianchini, Judit Fazekas-Singer, Ina Herrmann, Giulia Pellizzari, Ian D Haidl, Karin Hufnagl, Sophia N Karagiannis, Jean S Marshall, Erika Jensen-Jarolim

Open access · hybridAbstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Allergy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Jelena GotovinaComparative Medicine, The Interuniversity Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University of Vienna and University of Vienna, Vienna, Austria.ORCID 0000-0003-1503-5276
Rodolfo BianchiniComparative Medicine, The Interuniversity Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University of Vienna and University of Vienna, Vienna, Austria.ORCID 0000-0003-0351-6937
Judit Fazekas-SingerComparative Medicine, The Interuniversity Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University of Vienna and University of Vienna, Vienna, Austria.ORCID 0000-0002-8777-3502
Ina HerrmannComparative Medicine, The Interuniversity Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University of Vienna and University of Vienna, Vienna, Austria.ORCID 0000-0003-2772-9144
Giulia PellizzariSt John's Institute of Dermatology, School of Basic and Medical Biosciences, Guy's Cancer Centre, King's College London, London, UK.ORCID 0000-0003-0387-1912
Ian D HaidlDepartment of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.ORCID 0000-0002-5301-0822
Karin HufnaglComparative Medicine, The Interuniversity Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University of Vienna and University of Vienna, Vienna, Austria.ORCID 0000-0002-2288-2468
Sophia N KaragiannisBreast Cancer Now Unit, School of Cancer and Pharmaceutical Sciences, Guy's Cancer Centre, King's College London, London, UK.ORCID 0000-0002-4100-7810
Jean S MarshallDepartment of Microbiology and Immunology, Dalhousie University, Halifax, NS, Canada.ORCID 0000-0002-5642-1379
Erika Jensen-JarolimComparative Medicine, The Interuniversity Messerli Research Institute of the University of Veterinary Medicine Vienna, Medical University of Vienna and University of Vienna, Vienna, Austria.ORCID 0000-0003-4019-5765
University of Veterinary Medicine Vienna · ATDalhousie University · CAKing's College London · GB

Funding

Cancer Research UK C30122/A11527Cancer Research UK C30122/A15774CR UK//NIHR in England/DoH for Scotland, Wales and Northern Ireland Experimental Cancer Medicine Centre C10355/A15587Medical Research Council MR/L023091/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell DegranulationMast CellsEpinephrineHumansMacrophagesPhenotypeEpinephrineallergybeta2-adrenergic receptorepinephrineM2a macrophagesmast cell

Identifiers

PMID32246841
PMCPMC7687235
OpenAlexW3014096086

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.