Evidence map›Paper›PMID 32246815›Full record

ArticleThoracic cancer2020

Cantharidin-loaded functional mesoporous titanium peroxide nanoparticles for non-small cell lung cancer targeted chemotherapy combined with high effective photodynamic therapy.

Kun Zheng, Runze Chen, Yanxue Sun, Zhenquan Tan, Ye Liu, Xiao Cheng, Junke Leng, Zhaoming Guo, Pengcheng Xu

Open access · goldAbstract read
In one paragraph

Article in Thoracic cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. TiOJournal of materials science. Materials in medicine · 2024
    Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Nanoparticle Delivery Systems with Cell-Specific Targeting for Pulmonary Diseases.American journal of respiratory cell and molecular biology · 2021
    Review
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Kun ZhengSchool of Life Science and Medicine, Dalian University of Technology, Panjin, China.
Runze ChenSchool of Life Science and Medicine, Dalian University of Technology, Panjin, China.
Yanxue SunDepartment of Pharmaceutical Engineering, College of Pharmacy, Inner Mongolia Medical University, Hohhot, China.
Zhenquan TanSchool of Petroleum and Chemical Engineering, Dalian University of Technology, Panjin, China.
Ye LiuSchool of Life Science and Medicine, Dalian University of Technology, Panjin, China.
Xiao ChengSchool of Life Science and Medicine, Dalian University of Technology, Panjin, China.
Junke LengSchool of Life Science and Medicine, Dalian University of Technology, Panjin, China.
Zhaoming GuoSchool of Life Science and Medicine, Dalian University of Technology, Panjin, China.
Pengcheng XuDepartment of Pharmaceutical Engineering, College of Pharmacy, Inner Mongolia Medical University, Hohhot, China.ORCID 0000-0001-6888-1076
Dalian University of Technology · CNInner Mongolia Medical University · CN

Funding

Dalian Science and Technology Innovation Fund 2019J12GX045Fundamental Research Funds for the Central Universities DUT17RC(4)35National Natural Science Foundation of China 81760760 and 81603049Natural Science Foundation of Inner Mongolia Autonomous Region 2016MS0847Natural Science Foundation of Liaoning Province 2019-MS-059 and 20180550177Science and Technology Planning Project of Inner Mongolia Autonomous Region 201502101Scientific Research Planning Project of Health and Family Planning Commission of Inner Mongolia Autonomous Region 201701048
6 · The paper itself

Abstract

backgroundAlthough photodynamic therapy (PDT) has emerged as a potential alternative to conventional chemotherapy, the low reactive oxygen species (ROS) yield of the photosensitizer such as TiO

methodsWe used TiOx nanocomposite (YSA-PEG-TiO

resultsOur findings showed that the modification of YSA peptide improved the cytotoxicity of YSA-PEG-TiO

conclusionsYSA-PEG-TiO

Indexed as

PhotochemotherapyCantharidinCarcinoma, Non-Small-Cell LungEnzyme InhibitorsHumansLung NeoplasmsNanoparticlesPeroxidesPhotosensitizing AgentsReactive Oxygen SpeciesTitaniumTumor Cells, CulturedCantharidinEnzyme InhibitorsPeroxidesPhotosensitizing AgentsReactive Oxygen SpeciesTitaniumCantharidinnon-small cell lung cancerphotodynamic therapy (PDT)targeted deliverytitanium peroxide

Identifiers

PMID32246815
PMCPMC7262929
OpenAlexW3014961862

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.