Evidence map›Paper›PMID 32246615›Full record

ReviewJournal of biomedical optics2020

Parametric imaging of attenuation by optical coherence tomography: review of models, methods, and clinical translation.

Peijun Gong, Mitra Almasian, Gijs van Soest, Daniel de Bruin, Ton van Leeuwen, David Sampson, Dirk Faber

Open access · goldAbstract readReview
In one paragraph

Review in Journal of biomedical optics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 102 citations in OpenAlex.

  1. Article
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  4. Phantoms for use in optical coherence elastography.Journal of biomedical optics · 2026
    Review
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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Peijun GongThe Univ. of Western Australia, Australia.
Mitra AlmasianAmsterdam UMC, Univ. of Amsterdam, Netherlands.
Gijs van SoestErasmus MC, Netherlands.
Daniel de BruinAmsterdam UMC, Netherlands.
Ton van LeeuwenAmsterdam UMC, Netherlands.
David SampsonThe Univ. of Western Australia, Australia.
Dirk FaberAmsterdam UMC, Univ. of Amsterdam, Netherlands.
Amsterdam University Medical Centers · NLUniversity of Amsterdam · NLUniversity of Western Australia · AUErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

significanceOptical coherence tomography (OCT) provides cross-sectional and volumetric images of backscattering from biological tissue that reveal the tissue morphology. The strength of the scattering, characterized by an attenuation coefficient, represents an alternative and complementary tissue optical property, which can be characterized by parametric imaging of the OCT attenuation coefficient. Over the last 15 years, a multitude of studies have been reported seeking to advance methods to determine the OCT attenuation coefficient and developing them toward clinical applications.

aimOur review provides an overview of the main models and methods, their assumptions and applicability, together with a survey of preclinical and clinical demonstrations and their translation potential.

resultsThe use of the attenuation coefficient, particularly when presented in the form of parametric en face images, is shown to be applicable in various medical fields. Most studies show the promise of the OCT attenuation coefficient in differentiating between tissues of clinical interest but vary widely in approach.

conclusionsAs a future step, a consensus on the model and method used for the determination of the attenuation coefficient is an important precursor to large-scale studies. With our review, we hope to provide a basis for discussion toward establishing this consensus.

Indexed as

Tomography, Optical CoherenceCross-Sectional Studiesattenuation coefficientcardiologydermatologymultiple scatteringoncologyoptical coherence tomographysingle scattering

Identifiers

PMID32246615
PMCPMC7118361
OpenAlexW3014840259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.