ArticleThe British journal of surgery2020
Locoregional recurrences after transanal total mesorectal excision of rectal cancer during implementation.
Article in The British journal of surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.
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55 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Minimally Invasive and Open Gastrectomy for Gastric Cancer: A Systematic Review and Network Meta-Analysis of Randomized Clinical Trials.Annals of surgical oncology · 2023Pooled it
- The learning curve of laparoscopic, robot-assisted and transanal total mesorectal excisions: a systematic review.Surgical endoscopy · 2022Pooled it
- Trial
- Association between technical difficulty and patient prognosis after transanal total mesorectal excision for middle and low rectal cancer: a multicenter cohort study.Surgical endoscopy · 2026Article
- EUS-FNA improves diagnosis of extraluminal anastomotic recurrence after surgery.Surgical endoscopy · 2026Article
- Outcomes of transanal vs laparoscopic total mesorectal excision for mid and low rectal cancer under routine clinical practice conditions.Surgical endoscopy · 2026Article
- Long-term oncologic outcomes after transanal total mesorectal excision: a single-center cohort with a minimum of 5-year follow-up.Surgical endoscopy · 2026Article
- The transanal approach for lower rectal cancer: a propensity score-matched analysis.Surgery today · 2026Article
- Outcomes of transanal total mesorectal excision with ultra-low anterior resection: A single institute propensity-matched cohort study.Experimental and therapeutic medicine · 2026Article
- Essential Updates 2024-2026: Advances in Colorectal Cancer Surgery.Annals of gastroenterological surgery · 2026Review
- Impact of Hospital Volume on Local Recurrence of Rectal Cancer After Transanal Total Mesorectal Excision: A Nationwide Multicenter Cohort Study in Japan.Annals of surgical oncology · 2026Article
- Development and validation of an interpretable machine learning model for predicting postoperative complications after transanal total mesorectal excision: a multicenter study.Techniques in coloproctology · 2026Article
- Enhancing Surgical Efficiency and Cost-Effectiveness With TaTME-Combined Robot-Assisted Surgery for Lower Rectal Cancer.Annals of gastroenterological surgery · 2026Article
- Is Transanal total mesorectal excision (TME) as safe and effective as laparoscopic TME for low rectal cancer? A propensity score-matched analysis.Surgery today · 2026Article
- Current surgical treatment strategies and ongoing issues for locally recurrent rectal cancer.Japanese journal of clinical oncology · 2025Review
- Transanal total mesorectal excision for locally advanced rectal cancer following neoadjuvant chemoradiotherapy.Surgery today · 2025Article
- Anorectal and urogenital functional outcome after robotic and transanal total mesorectal excision for rectal cancer: a propensity score-matched analysis.Techniques in coloproctology · 2025Article
- Metabolic bariatric surgery generates substantial, sustained weight loss and health improvement in a real-world setting.ANZ journal of surgery · 2025Observational
- Clinical using of innovative biodegradable stent with extension sleeve in Ta_tme for low rectal cancer with high risk of anastomotic leakage.Scientific reports · 2025Article
- Comparative efficacy analysis of laparoscopic-assisted transanal total mesorectal excisionWorld journal of gastrointestinal surgery · 2025Article
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22 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTransanal total mesorectal excision (TaTME) has been proposed as an approach in patients with mid and low rectal cancer. The TaTME procedure has been introduced in the Netherlands in a structured training pathway, including proctoring. This study evaluated the local recurrence rate during the implementation phase of TaTME.
methodsOncological outcomes of the first ten TaTME procedures in each of 12 participating centres were collected as part of an external audit of procedure implementation. Data collected from a cohort of patients treated over a prolonged period in four centres were also collected to analyse learning curve effects. The primary outcome was the presence of locoregional recurrence.
resultsThe implementation cohort of 120 patients had a median follow up of 21·9 months. Short-term outcomes included a positive circumferential resection margin rate of 5·0 per cent and anastomotic leakage rate of 17 per cent. The overall local recurrence rate in the implementation cohort was 10·0 per cent (12 of 120), with a mean(s.d.) interval to recurrence of 15·2(7·0) months. Multifocal local recurrence was present in eight of 12 patients. In the prolonged cohort (266 patients), the overall recurrence rate was 5·6 per cent (4·0 per cent after excluding the first 10 procedures at each centre).
conclusionTaTME was associated with a multifocal local recurrence rate that may be related to suboptimal execution rather than the technique itself. Prolonged proctoring, optimization of the technique to avoid spillage, and quality control is recommended.
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