ReviewJapanese journal of radiology2020
FDG-PET/CT imaging findings of hepatic tumors and tumor-like lesions based on molecular background.
Review in Japanese journal of radiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 40 citations in OpenAlex.
- Hepatic Vascular Shunts Mimicking Malignant Lesions onMolecular imaging and radionuclide therapy · 2026Article
- Tumor Characterization Using [Pharmaceuticals (Basel, Switzerland) · 2026Article
- Preventing false positive imaging diagnosis of HCC: differentiating HCC from mimickers and practical strategies.Journal of liver cancer · 2025Article
- Analysis of the best time-point for 18F-FDG PET/CT delayed imaging in patients of small colorectal cancer liver metastasis with hypothyroidism based on diagnostic efficacy and image standardized uptake values.Annals of nuclear medicine · 2025Article
- Preliminary study on detection and diagnosis of focal liver lesions based on a deep learning model using multimodal PET/CT images.European journal of radiology open · 2025Article
- GLUT-1-negative Choroidal Malignant Melanoma with Liver Metastasis Recurrence 12 Years after Surgery without FDG Accumulation in a Recurrent Lesion on FDG-PET/CT.Internal medicine (Tokyo, Japan) · 2025Article
- Correlation of preoperative 18F-FDG-PET/CT tumor staging and maximum standardized uptake values with preoperative CT, postoperative tumor classification, and histopathological parameters of oral squamous cell carcinoma.Clinical oral investigations · 2025Article
- In Vivo Time-Resolved Fluorescence Detection of Liver Cancer Supported by Machine Learning.Lasers in surgery and medicine · 2024Article
- A paradigm shift in diagnosis and treatment innovation for mucinous cystic neoplasms of the liver.Scientific reports · 2024Article
- Patlak Slope versus Standardized Uptake Value Image Quality in an Oncologic PET/CT Population: A Prospective Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2024Article
- A prospective study ofAnnals of nuclear medicine · 2024Article
- Biodistribution and radiation dosimetry of multiple tracers on total-body positron emission tomography/computed tomography.Quantitative imaging in medicine and surgery · 2023Article
- Is Prone Position [Diagnostics (Basel, Switzerland) · 2023Article
- Incidental combined hepatocellular-cholangiocarcinoma in liver transplant patients: Does it have a worse prognosis?Hepatology forum · 2023Article
- Emerging theragnostic radionuclide applications for hepatocellular carcinoma.Frontiers in nuclear medicine · 2023Review
- An activated excretion-retarded tumor imaging strategy towards metabolic organs.Bioactive materials · 2022Article
- Schwannoma in and around the porta hepatis: radiological features in eight cases and literature review.Abdominal radiology (New York) · 2022Review
- Hepatic Positron Emission Tomography: Applications in Metabolism, Haemodynamics and Cancer.Metabolites · 2022Review
- Morphological, dynamic and functional characteristics of liver pseudolesions and benign lesions.La Radiologia medica · 2022Review
- Case report: Rare isolated cystic hepatic metastasis of a patient with squamous cell lung carcinoma history and the prognosis.Frontiers in oncology · 2022Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The usefulness of whole-body 18-fluoro-2-deoxyglucose (FDG)-fluorodeoxyglucose positron emission (PET)/computed tomography (CT) is established for assessment of disease staging, detection of early disease recurrence, therapeutic evaluation, and predicting prognosis in various malignancies; and for evaluating the spread of inflammation. However, the role of FDG-PET/CT for the liver is limited because CT and magnetic resonance imaging (MRI) can provide an accurate diagnosis of most tumors. In addition, in other potentially useful roles there are several pitfalls in the interpretation of FDG uptake in PET/CT imaging. Accurate evaluation demands knowledge of the FDG uptake of each lesion, including potential negative and positive uptakes, and requires an understanding of the underlying background of the molecular mechanisms. The degree of FDG uptake is dependent on cellular metabolic rate and the expression of glucose transporter, hexokinase, and glucose-6-phosphatase, which in turn are closely affected by biological characteristics such as pathological category (e.g., adenocarcinoma, squamous cell carcinoma, small cell cancer, transitional cell cancer, neuroendocrine tumor, sarcoma, lymphoma), tumor differentiation, histological behavior (e.g., solid, cystic, mucinous), and intratumoral alterations (e.g., necrosis, degeneration, hemorrhage). Correlation with the CT and MRI findings, which also precisely depict the pathological findings, is important to avoid misdiagnosis.
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