Evidence map›Paper›PMID 32246250›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2020

How long is long enough? Good neurologic outcome in out-of-hospital cardiac arrest survivors despite prolonged resuscitation: a retrospective cohort study.

Simon Braumann, Felix Sebastian Nettersheim, Christopher Hohmann, Tobias Tichelbäcker, Martin Hellmich, Anton Sabashnikov, Ilija Djordjevic, Joana Adler, Richard Julius Nies, Dennis Mehrkens and 5 more

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Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Simon BraumannDivision of Cardiology, Pneumology, Angiology and Intensive Care, Department of Internal Medicine III, University of Cologne, 50924, Cologne, Germany.
Felix Sebastian NettersheimDivision of Cardiology, Pneumology, Angiology and Intensive Care, Department of Internal Medicine III, University of Cologne, 50924, Cologne, Germany.
Christopher HohmannDivision of Cardiology, Pneumology, Angiology and Intensive Care, Department of Internal Medicine III, University of Cologne, 50924, Cologne, Germany.
Tobias TichelbäckerDivision of Cardiology, Pneumology, Angiology and Intensive Care, Department of Internal Medicine III, University of Cologne, 50924, Cologne, Germany.
Martin HellmichInstitute of Medical Statistics and Computational Biology (IMSB), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Anton SabashnikovDepartment of Cardiothoracic Surgery, Heart Center of the University of Cologne, Cologne, Germany.
Ilija DjordjevicDepartment of Cardiothoracic Surgery, Heart Center of the University of Cologne, Cologne, Germany.
Joana AdlerDivision of Cardiology, Pneumology, Angiology and Intensive Care, Department of Internal Medicine III, University of Cologne, 50924, Cologne, Germany.
Richard Julius NiesDivision of Cardiology, Pneumology, Angiology and Intensive Care, Department of Internal Medicine III, University of Cologne, 50924, Cologne, Germany.
Dennis MehrkensDivision of Cardiology, Pneumology, Angiology and Intensive Care, Department of Internal Medicine III, University of Cologne, 50924, Cologne, Germany.
Samuel LeeDivision of Cardiology, Pneumology, Angiology and Intensive Care, Department of Internal Medicine III, University of Cologne, 50924, Cologne, Germany.
Robert StanglDepartment of Emergency Medicine, Fire Department City of Cologne, Cologne, Germany.
Hannes ReuterDivision of Cardiology, Pneumology, Angiology and Intensive Care, Department of Internal Medicine III, University of Cologne, 50924, Cologne, Germany.
Stephan BaldusDivision of Cardiology, Pneumology, Angiology and Intensive Care, Department of Internal Medicine III, University of Cologne, 50924, Cologne, Germany.
Christoph AdlerDivision of Cardiology, Pneumology, Angiology and Intensive Care, Department of Internal Medicine III, University of Cologne, 50924, Cologne, Germany. Christoph.adler@uk-koeln.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite all efforts, mortality of out of hospital cardiac arrest (OHCA) remains high. Patients with OHCA due to a primary shockable rhythm typically have a better prognosis. However, outcome worsens if return of spontaneous circulation (ROSC) cannot be achieved quickly. There is insufficient evidence for maximum duration of resuscitation in these patients and it is unclear, which patients profit from transport under ongoing CPR.

objectiveInvestigate predictors for favourable neurologic outcome in OHCA patients with presumed cardiac cause due to refractory shockable rhythm (rSR).

methodsRetrospective analysis of OHCA patients that presented to a tertiary hospital due to a rSR.

resultsOne hundred seventy-five OHCA patients with presumed cardiac cause due to rSR were included. Overall hospital mortality was 50% and 83% of initial survivors were discharged with a good neurologic outcome [cerebral performance category (CPC) 1-2]. In patients with a time from cardiac arrest to ROSC of > 45 min, 18% survived to CPC 1-2. Independent predictors for good neurologic outcome were age, lower no-flow time and lower serum lactate levels at hospital arrival.

conclusionIn an urban setting, a significant proportion of OHCA patients with rSR can survive to a good neurologic outcome, despite very long time to ROSC.

Indexed as

RegistriesCardiopulmonary ResuscitationCoughEmergency Medical ServicesFemaleFollow-Up StudiesGermanyHospital MortalityHumansMaleMiddle AgedOut-of-Hospital Cardiac ArrestPrognosisRetrospective StudiesTime FactorsNeurologic outcomeOHCAOngoing CPRRefractory cardiac arrestRefractory shockable rhythm

Identifiers

PMID32246250

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.