Evidence map›Paper›PMID 32246193›Full record

ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2020

Suprasellar central nervous system ganglioneuroblastoma: a case in a 9-year-old child and review of the literature.

Oliver D Mrowczynski, Jessica R Lane, Charles S Specht, Robert J Greiner, Mark R Iantosca, Elias B Rizk

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Primary intracranial pediatric ganglioneuroblastoma-report of two cases and review of an unusual masquerader.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Oliver D MrowczynskiDepartment of Neurosurgery, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA. omrowczynski@pennstatehealth.psu.edu.
Jessica R LaneDepartment of Neurosurgery, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.
Charles S SpechtDepartment of Neurosurgery, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.
Robert J GreinerDepart of Pediatric Hematology/Oncology, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.
Mark R IantoscaDepartment of Neurosurgery, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.
Elias B RizkDepartment of Neurosurgery, Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA.
Pennsylvania State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIntracranial ganglioneuroblastomas are incredibly rare neuroectodermal tumors with only 8 described cases total, 5 of those having imaging findings

methodsHere we present a 9-year-old female patient with 4 months progressive headaches, personality changes, and vomiting. We also present a review of the current literature of intracranial ganglioneuroblastomas.

resultsImaging demonstrated a partially calcified suprasellar mass measuring 4.6 × 6.3 × 5 cm composed of both solid and cystic components, diagnosed to be a ganglioneuroblastoma, with mass effect on the lateral and 3rd ventricles, with a midline shift of right to left of 6-7 mm. She was treated with subtotal surgical resection, an intensive chemotherapeutic regimen, and radiation and has no residual disease on imaging 1 year and 4 months status post-surgery.

conclusionTo our knowledge, this is the first case of a ganglioneuroblastoma to mimic a craniopharyngioma based upon imaging findings and suprasellar location. As these cases are extremely rare, an optimal therapeutic regimen has not been defined. However, a combination of surgical resection, chemotherapy, and radiation therapy can be effective, as shown here with successful treatment and no evidence of residual disease.

Indexed as

CraniopharyngiomaGanglioneuroblastomaPituitary NeoplasmsSupratentorial NeoplasmsCentral Nervous SystemChildFemaleHumansCentral nervous system ganglioneuroblastomaGanglioneuromaNeuroblastomaReviewSuprasellar

Identifiers

PMID32246193
OpenAlexW3014192847

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.