Evidence map›Paper›PMID 32245973›Full record

ArticleNature communications2020

Functional brain network reconfiguration during learning in a dynamic environment.

Chang-Hao Kao, Ankit N Khambhati, Danielle S Bassett, Matthew R Nassar, Joseph T McGuire, Joshua I Gold, Joseph W Kable

Abstract read
In one paragraph

Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. Triple network dynamics and future alcohol consumption in adolescents.Alcohol, clinical & experimental research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chang-Hao KaoDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, 19104, USA. chakao@sas.upenn.edu.ORCID http://orcid.org/0000-0002-2928-302X
Ankit N KhambhatiDepartment of Neurological Surgery, University of California, San Francisco, CA, 94122, USA.
Danielle S BassettDepartment of Bioengineering, University of Pennsylvania, Philadelphia, PA, 19104, USA.ORCID http://orcid.org/0000-0002-6183-4493
Matthew R NassarDepartment of Neuroscience, Brown University, Providence, RI, 02912, USA.ORCID http://orcid.org/0000-0002-5397-535X
Joseph T McGuireDepartment of Psychological and Brain Sciences, Boston University, Boston, MA, 02215, USA.ORCID http://orcid.org/0000-0001-6259-0809
Joshua I GoldDepartment of Neuroscience, University of Pennsylvania, Philadelphia, PA, 19104, USA.ORCID http://orcid.org/0000-0002-6018-0483
Joseph W KableDepartment of Psychology, University of Pennsylvania, Philadelphia, PA, 19104, USA. kable@psych.upenn.edu.

Funding

Individual, age-dependent differences in ACC-mediated adaptive decision makingR01MH098899 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI GOLD, JOSHUA I, KABLE, JOSEPH W · 2012 to 2014
$2.0M
Cognitive and Molecular Challenges to Statistical Inference Across Healthy Aging.R00AG054732 · NIA · BROWN UNIVERSITY · PI NASSAR, MATTHEW · 2019 to 2021
$744k
NIA NIH HHS R00 AG054732NIMH NIH HHS R01 MH098899
6 · The paper itself

Abstract

When learning about dynamic and uncertain environments, people should update their beliefs most strongly when new evidence is most informative, such as when the environment undergoes a surprising change or existing beliefs are highly uncertain. Here we show that modulations of surprise and uncertainty are encoded in a particular, temporally dynamic pattern of whole-brain functional connectivity, and this encoding is enhanced in individuals that adapt their learning dynamics more appropriately in response to these factors. The key feature of this whole-brain pattern of functional connectivity is stronger connectivity, or functional integration, between the fronto-parietal and other functional systems. Our results provide new insights regarding the association between dynamic adjustments in learning and dynamic, large-scale changes in functional connectivity across the brain.

Indexed as

Models, NeurologicalAdolescentAdultConnectomeFemaleFrontal LobeHumansLearningMagnetic Resonance ImagingMaleNerve NetNeural PathwaysParietal LobeUncertaintyYoung Adult

Identifiers

PMID32245973
PMCPMC7125157

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.