Evidence map›Paper›PMID 32245841›Full record

ArticleRegional anesthesia and pain medicine2020

Consensus practice guidelines on interventions for lumbar facet joint pain from a multispecialty, international working group.

Steven P Cohen, Arun Bhaskar, Anuj Bhatia, Asokumar Buvanendran, Tim Deer, Shuchita Garg, W Michael Hooten, Robert W Hurley, David J Kennedy, Brian C McLean and 11 more

5 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Regional anesthesia and pain medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 152 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
152citing papers in PubMed, 8 pooled it
26.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04494698 nacompletednot on this mapstarted 2022, after this paper: background citation

Addressing Pain and Disability From Low Back Pain With an External Multimodal Neuromodulation Device

TypeinterventionalSponsorMMJ Labs LLCRan2022 to 2025Enrolled160ConditionsAcute Low-back Pain, Chronic Low-back Pain, Pain, IntractableArmsDuotherm VibraCool Back Device, TENS 8-channel unit
NCT04542798 naunknown statusnot on this map

Central Sensitization and Aberrant Nerve Sprouting Possible Explanations for RFA Failure of MBDR in CLBP of FJ Origin: CRF Versus WCRF or PRF-DRG Randomized Clinical Trial

TypeinterventionalSponsorHospital General Universitario de ValenciaRan2020 to 2024Enrolled80ConditionsLow Back Pain, Recurrent, Neuropathic Pain, Facet Joint Pain, Central SensitisationArmsRadiofrequency COSMAN
NCT06804551 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

A Single-center, Prospective, Double-blind, Randomized Controlled Trial Evaluating Iovera° Lumbar Medial Branch Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Facet-mediated Chronic Low Back Pain

TypeinterventionalSponsorUniversity of Kansas Medical CenterRan2025 to 2027Enrolled30ConditionsChronic Low-back PainArmsiovera system, Radiofrequency ablation alone
NCT06934421 recruitingnot on this mapstarted 2025, after this paper: background citation

Segurança e eficácia de Nova Abordagem Ecoguiada de ablação Por radiofrequência Dos Nervos Geniculados

TypeobservationalSponsorCentro Hospitalar Universitario do AlgarveRan2025 to 2031Enrolled60ConditionsOsteoarthritis Knee PainArmsUltrasound-Guided Genicular Nerve Radiofrequency Ablation
NCT07214844 narecruitingnot on this mapstarted 2026, after this paper: background citation

A Prospective, Randomized, Assessor Blind, Active-controlled, Single-center Study to Evaluate the Efficacy of Iovera Lumbar Medial Branch Cryoneurolysis Versus Radiofrequency Ablation for the Treatment of Facet-mediated Chronic Low Back Pain

TypeinterventionalSponsorMontefiore Medical CenterRan2026 to 2028Enrolled110ConditionsLow Back Pain, ChronicArmsIovera Medial Branch Cryoneurolysis, Radiofrequency ablation (RFA)
3 · Its place in the literature

Who cites it

152 citing papers in PubMed, 8 syntheses or guidelines pooled it, 348 citations in OpenAlex.

  1. Pooled it
  2. The Implementation of Persistent Spinal Pain Syndrome (PSPS): Mechanism-Based Recommendations.Pain practice : the official journal of World Institute of Pain · 2026
    Guideline
  3. Effectiveness of single-photon emission computed tomography (SPECT/SPECT-CT) in predicting therapeutic response to facet interventions for facet joint-related low back pain: A systematic review and Meta-Analysis.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Pooled it
  4. Guideline
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92 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

21 authors at 17 institutions in 6 countries.

Steven P CohenAnesthesiology, Pain Medicine Division, Johns Hopkins School of Medicine, Baltimore, Maryland, USA scohen40@jhmi.edu.ORCID 0000-0001-5928-2127
Arun BhaskarAnesthesiology, Imperial College Healthcare NHS Trust Haemodialysis Clinic Hayes Satellite Unit, Hayes, UK.
Anuj BhatiaAnesthesia and Pain Management, University of Toronto and University Health Network-Toronto Western Hospital, Toronto, Ontario, Canada.
Asokumar BuvanendranAnesthesiology, Rush University Medical Center, Chicago, Illinois, USA.
Tim DeerSpine & Nerve Centers, Charleston, West Virginia, USA.
Shuchita GargAnesthesiology, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
W Michael HootenAnesthesiology, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0001-5645-6355
Robert W HurleyAnesthesiology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
David J KennedyPhysical Medicine & Rehabilitation, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
Brian C McLeanAnesthesiology, Tripler Army Medical Center, Tripler Army Medical Center, Hawaii, USA.
Jee Youn MoonDept of Anesthesiology, Seoul National University College of Medicine, Seoul, The Republic of Korea.
Samer NarouzeCenter for Pain Medicine, Summa Western Reserve Hospital, Cuyahoga Falls, Ohio, USA.
Sanjog PangarkarDept of Physical Medicine and Rehabilitation, VA Greater Los Angeles Healthcare System, Los Angeles, California, USA.
David Anthony ProvenzanoPain Diagnostics and Interventional Care, Sewickley, Pennsylvania, USA.
Richard RauckCarolinas Pain Institute, Winston Salem, North Carolina, USA.
B Todd SitzmanAdvanced Pain Therapy, Hattiesburg, Mississippi, USA.
Matthew SmuckDept.of Orthopaedic Surgery, Division of Physical Medicine & Rehabilitation, Stanford Medicine, Stanford, California, USA.
Jan van ZundertAnesthesiology, Critical Care and Multidisciplinary Pain Center, Ziekenhuis Oost-Limburg, Lanaken, Belgium.ORCID 0000-0002-5389-2036
Kevin VorenkampAnesthesiology, Duke Medicine, Durham, North Carolina, USA.
Mark S WallaceAnesthesiology, UCSD Medical Center-Thornton Hospital, San Diego, California, USA.
Zirong ZhaoNeurology, VA Healthcare Center District of Columbia, Washington, District of Columbia, USA.
Carolinas Pain Institute · USImperial College Healthcare NHS Trust · GBJohns Hopkins University · USMaastricht University · NLMayo Clinic · USRush University Medical Center · USSeoul National University · KRStanford Medicine · USThe Spine & Nerve Centers of the Virginias · USTripler Army Medical Center · USUniversity Health Network · CAUniversity of Cincinnati Medical Center · USVA Greater Los Angeles Healthcare System · USVanderbilt University · USWake Forest University · USWashington DC VA Medical Center · USWestern Reserve Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe past two decades have witnessed a surge in the use of lumbar facet blocks and radiofrequency ablation (RFA) to treat low back pain (LBP), yet nearly all aspects of the procedures remain controversial.

methodsAfter approval by the Board of Directors of the American Society of Regional Anesthesia and Pain Medicine, letters were sent to a dozen pain societies, as well as representatives from the US Departments of Veterans Affairs and Defense. A steering committee was convened to select preliminary questions, which were revised by the full committee. Questions were assigned to 4-5 person modules, who worked with the Subcommittee Lead and Committee Chair on preliminary versions, which were sent to the full committee. We used a modified Delphi method, whereby the questions were sent to the committee en bloc and comments were returned in a non-blinded fashion to the Chair, who incorporated the comments and sent out revised versions until consensus was reached.

results17 questions were selected for guideline development, with 100% consensus achieved by committee members on all topics. All societies except for one approved every recommendation, with one society dissenting on two questions (number of blocks and cut-off for a positive block before RFA), but approving the document. Specific questions that were addressed included the value of history and physical examination in selecting patients for blocks, the value of imaging in patient selection, whether conservative treatment should be used before injections, whether imaging is necessary for block performance, the diagnostic and prognostic value of medial branch blocks (MBB) and intra-articular (IA) injections, the effects of sedation and injectate volume on validity, whether facet blocks have therapeutic value, what the ideal cut-off value is for a prognostic block, how many blocks should be performed before RFA, how electrodes should be oriented, the evidence for larger lesions, whether stimulation should be used before RFA, ways to mitigate complications, if different standards should be applied to clinical practice and clinical trials and the evidence for repeating RFA (see table 12 for summary).

conclusionsLumbar medial branch RFA may provide benefit to well-selected individuals, with MBB being more predictive than IA injections. More stringent selection criteria are likely to improve denervation outcomes, but at the expense of more false-negatives. Clinical trials should be tailored based on objectives, and selection criteria for some may be more stringent than what is ideal in clinical practice.

Indexed as

Low Back PainZygapophyseal JointArthralgiaConsensusHumansInjections, Intra-Articularchronic pain: back paincomplicationsinterventional pain managementpain medicineradiofrequency ablation

Identifiers

PMID32245841
PMCPMC7362874
OpenAlexW3014618885

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.