Evidence map›Paper›PMID 32245797›Full record

ArticleJournal of the American Society of Nephrology : JASN2020

Interaction between Epithelial Sodium Channel

Ali Sassi, Yubao Wang, Alexandra Chassot, Olga Komarynets, Isabelle Roth, Valérie Olivier, Gilles Crambert, Eva Dizin, Emilie Boscardin, Edith Hummler and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Review
  3. Claudin-3 is expressed at theFrontiers in physiology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Frontiers in microbiology · 2024
    Article
  10. Article
  11. Article
  12. The role of claudins in homeostasis.Nature reviews. Nephrology · 2023
    Review
  13. Article
  14. Article
  15. Claudins in kidney health and disease.Kidney research and clinical practice · 2022
    Article
  16. Review
  17. Frontiers in immunology · 2021
    Article
  18. Sex differences in solute transport along the nephrons: effects of NaAmerican journal of physiology. Renal physiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ali SassiDepartment of Cellular Physiology and Metabolism, University of Geneva, University Medical Center, Geneva, Switzerland.ORCID 0000-0002-3194-777X
Yubao WangDepartment of Cellular Physiology and Metabolism, University of Geneva, University Medical Center, Geneva, Switzerland.ORCID 0000-0002-8063-6628
Alexandra ChassotDepartment of Cellular Physiology and Metabolism, University of Geneva, University Medical Center, Geneva, Switzerland.
Olga KomarynetsDepartment of Cellular Physiology and Metabolism, University of Geneva, University Medical Center, Geneva, Switzerland.
Isabelle RothDepartment of Cellular Physiology and Metabolism, University of Geneva, University Medical Center, Geneva, Switzerland.
Valérie OlivierDepartment of Cellular Physiology and Metabolism, University of Geneva, University Medical Center, Geneva, Switzerland.ORCID 0000-0001-9308-4853
Gilles CrambertSorbonne University, Unité Mixte de Recherche (UMR) S1138, Cordeliers Research Center, Paris, France.
Eva DizinDepartment of Cellular Physiology and Metabolism, University of Geneva, University Medical Center, Geneva, Switzerland.
Emilie BoscardinNational Center of Competence in Research Kidney Control of Homeostasis (Kidney.CH), Zurich, Switzerland.
Edith HummlerNational Center of Competence in Research Kidney Control of Homeostasis (Kidney.CH), Zurich, Switzerland.
Eric FerailleDepartment of Cellular Physiology and Metabolism, University of Geneva, University Medical Center, Geneva, Switzerland Eric.Feraille@unige.ch.
University of Geneva · CHCenter for Pediatric Endocrinology Zurich · CHSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWater and solute transport across epithelia can occur

methodsTo investigate whether transcellular sodium transport controls tight-junction composition and paracellular permeability

resultsOverexpression or silencing of the ENaC

conclusionsOur data reveal the specific coupling between ENaC

Indexed as

Gene Expression RegulationAmilorideAnimalsBiological TransportCells, CulturedChloridesClaudinsEpithelial Sodium ChannelsGene SilencingIon TransportKidney Tubules, CollectingMiceMice, KnockoutRecombinant ProteinsRNA, MessengerSodiumAmiloridebenzamilChloridesclaudin 8ClaudinsEpithelial Sodium ChannelsRecombinant ProteinsRNA, MessengerScnn1g protein, mouseSodiumepithelial sodium channelparacellular ion permeabilityprincipal cellsodium reabsorptiontight junction

Identifiers

PMID32245797
PMCPMC7217417
OpenAlexW3014789571

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.