ArticleBMC pulmonary medicine2020
Diagnostic procedure for idiopathic eosinophilic pleural effusion: a single-center experience.
Article in BMC pulmonary medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Eosinophilic pleural effusion due toRespiratory medicine case reports · 2024Article
- Incidence, aetiology and clinical features of eosinophilic pleural effusion: a retrospective study.BMC pulmonary medicine · 2021Article
- Idiopathic eosinophilic pleurisy: A practical diagnostic approach.Respiratory medicine case reports · 2021Article
- Valproic acid-induced eosinophilic pleural effusion: An uncommon occurrence.Lung India : official organ of Indian Chest SocietyArticle
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundEosinophilic pleural effusion (EPE) is attributed to several well-recognised causes. However, some patients remain idiopathic, even after thorough clinical work-up. The present study aimed to better characterize idiopathic EPE (IEPE) and to outline the diagnostic procedure for this disease.
methodsComplete clinical data of 11 consecutive patients with IEPE were prospectively collected and analysed. Preliminary diagnostic procedure of IEPE in our hospital was performed.
resultsAll the 11 patients had respiratory symptoms and unilateral pleural effusion (PE) occurred in 4 patients. The mean percentage of eosinophils in PE was 22.4% (range, 12.4-50.5%). Lactate dehydrogenase, adenosine deaminase, proteins and carcinoembryonic antigen in PE were 246.0 U/L (range, 89.8-421.9 U/L), 13.8 U/L (range, 1.8-24.0 U/L), 42.6 g/dl (range, 32.8-52.6 g/dl) and 2.17 mg/mL (range, 0.46-4.31 mg/mL), respectively. Parasite-specific IgG antibody in blood and parasite eggs in stool were both negative. No evidence of tuberculosis or malignancy was observed in pleural biopsy. Symptoms and abnormal pulmonary imaging were eliminated after glucocorticoid use.
conclusionsIEPE is a diagnosis of exclusion. Patients with EPE without a clear cause should be asked to provided complete medical, surgical and drug-related histories. A thorough work-up is essential. Moreover, we recommend follow-up after the use of glucocorticoid until effusion resolves.
trial registrationGYFYY. Registration No: GYFYY20150901221. Registered time: 1 September 2015. Date of enrolment of the first participant to the trial: 22 January 2016.
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