ArticleBMC nephrology2020
Association of acute kidney injury with readmissions after hospitalization for acute exacerbation of chronic obstructive pulmonary disease: a population-based study.
Article in BMC nephrology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 13 citations in OpenAlex.
- Social Determinants of Health and ESKD among Survivors of Critical Illness and Acute Kidney Injury.Clinical journal of the American Society of Nephrology : CJASN · 2026Observational
- Exploring the causal relationship between COPD and AKI: A bidirectional Mendelian randomization approach.Medicine · 2026Article
- Bacterial Pneumonia and Acute Kidney Injury: Association and Impact on Outcomes of Patients Hospitalized for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (COPD) in the United States.The open respiratory medicine journal · 2026Article
- Risk prediction for acute kidney disease and adverse outcomes in patients with chronic obstructive pulmonary disease: an interpretable machine learning approach.Renal failure · 2025Article
- Impact of early acute kidney injury on 30-day mortality in intensive care unit patients with chronic obstructive pulmonary disease: a retrospective study using MIMIC-IV.Journal of thoracic disease · 2025Article
- The burden of acute kidney disease: an epidemiological review and importance of follow-up care.Clinical kidney journal · 2025Review
- Hospitalized acute exacerbation in chronic obstructive pulmonary disease - impact on long-term renal outcomes.Respiratory research · 2024Article
- Prognostic Value of Leukocyte-Based Risk Model for Acute Kidney Injury Prediction in Critically Ill Acute Exacerbation of Chronic Obstructive Pulmonary Disease Patients.International journal of chronic obstructive pulmonary disease · 2024Article
- Respiratory Specialist Visits Before Admissions with COPD Exacerbation are Linked to Improved Management and Outcomes.International journal of chronic obstructive pulmonary disease · 2024Observational
- Hospitalisation Due to Community-Acquired Acute Kidney Injury and the Role of Medications: A Retrospective Audit.Journal of clinical medicine · 2023Article
- Long-term consequences of acute kidney injury: a narrative review.Clinical kidney journal · 2021Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundLittle is known about the relationship between acute kidney injury (AKI) and outcomes after acute exacerbation of chronic obstructive pulmonary disease (AECOPD). We aimed to investigate associations between AKI and readmission risks after hospitalization for AECOPD.
methodsA retrospective, population-based cohort study using State Inpatient Databases from seven U.S. states (Arkansas, California, Florida, Iowa, Nebraska, New York, and Utah) from 2010 through 2013. We identified all adults (aged ≥40 years) hospitalized for AECOPD during the study period. Among them, we further identified patients with a concurrent diagnosis of new AKI. The outcome measures were any-cause readmissions within 30 days and 90 days after hospitalization for AECOPD. To determine associations between AKI and readmission risk, we constructed Cox proportional hazards models examining the time-to-readmission. We also identified the primary reason of readmission.
resultsWe identified 356,990 patients hospitalized for AECOPD. The median age was 71 years and 41.9% were male. Of these, 24,833 (7.0%) had a concurrent diagnosis of AKI. Overall, patients with AKI had significantly higher risk of 30-day all-cause readmission compared to those without AKI (hazard ratio 1.47; 95% CI 1.43-1.51; P < 0.001). Likewise, patients with AKI had significantly higher risk of 90-day all-cause readmission (hazard ratio 1.35; 95% CI 1.32-1.38; P < 0.001). These associations remained significant after adjustment for confounders (both P < 0.05). Additionally, patients with AKI were likely to be readmitted for non-respiratory reasons including sepsis, acute renal failure, and congestive heart failure.
conclusionsAmong patients hospitalized for AECOPD, patients with AKI were at higher risk of 30-day and 90-day readmission, particularly with non-respiratory reasons.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.