ArticleBMC gastroenterology2020
Incidence, aetiology and related comorbidities of cirrhosis: a Swedish population-based cohort study.
Article in BMC gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Navigating TIPS in the era of ageing and metabolic comorbidity: a contemporary narrative review of risk, resilience, and outcomes.Gastroenterology report · 2026Review
- The association between childhood obesity and major adverse liver outcomes in adolescence and young adulthood.JHEP reports : innovation in hepatology · 2025Article
- Novel Viral Sequences in a Patient with Cryptogenic Liver Cirrhosis Revealed by Serum Virome Sequencing.Viruses · 2025Article
- Assessment of Drug-related Problems among Patients of Chronic liver Disease in a Tertiary Care Hospital.Ethiopian journal of health sciences · 2024Observational
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- Development and validation of a case definition to estimate the prevalence and incidence of cirrhosis in pan-Canadian primary care databases.Canadian liver journal · 2023Article
- The Association between Birthweight and Use of Cardiovascular Medications: The Role of Health Behaviors.Journal of cardiovascular development and disease · 2023Article
- Review
- Feeling safe or falling through the cracks-Patients' experiences of healthcare in cirrhosis illness: A qualitative study.PloS one · 2023Article
- Epidemiology of liver cirrhosis and associated complications: Current knowledge and future directions.World journal of gastroenterology · 2022Review
- Article
- Hepatitis C virus: A critical approach to who really needs treatment.World journal of hepatology · 2022Review
- An update on the genetics of alcoholic liver disease.Frontiers in gastroenterology (Lausanne, Switzerland) · 2022Review
- Differences in complications between hepatitis B-related cirrhosis and alcohol-related cirrhosis.Open medicine (Warsaw, Poland) · 2022Article
- Genetic polymorphisms related to the vitamin D pathway in patients with cirrhosis with or without hepatocellular carcinoma (HCC).Ecancermedicalscience · 2022Article
- Managing medicines in alcohol-associated liver disease: a practical review.Australian prescriber · 2021Review
- Compound Sarcopenia in Hospitalized Patients with Cirrhosis Worsens Outcomes with Increasing Age.Nutrients · 2021Article
- Platelet count can predict the grade of esophageal varices in cirrhotic patients: a cross-sectional study.F1000Research · 2021Article
- Socioeconomic and marital status among liver cirrhosis patients and associations with mortality: a population-based cohort study in Sweden.BMC public health · 2020Article
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5 authors.
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Abstract
backgroundThe incidence of cirrhosis for individuals in Sweden has previously been reported as stable/low among European countries. However, Swedish population-based studies are scarce and none of them included data from the most recent decade (2010-2019). We aimed to describe the incidence and aetiology of cirrhosis in the Halland region from 2011 to 2018, and to describe the severity and prevalence of liver-related complications and other primary comorbidities at the time of cirrhosis diagnosis.
methodsWe conducted a retrospective cohort study of all patients with cirrhosis in Halland, which has a population of 310,000 inhabitants. Medical records and histopathology registries were reviewed.
resultsA total of 598 patients with cirrhosis were identified. The age-standardised incidence was estimated at 23.2 per 100,000 person-years (95% CI 21.3-25.1), 30.5 (95% CI 27.5-33.8) for men and 16.4 (95% CI 14.3-18.7) for women. When stratified by age, the highest incidence rates were registered at age 60-69 years. Men had a higher incidence rate for most age groups when compared to women. The most common aetiology was alcohol (50.5%), followed by cryptogenic cirrhosis (14.5%), hepatitis C (13.4%), and non-alcoholic fatty liver disease (5.7%). Most patients had at least one liver-related complication at diagnosis (68%). The most common comorbidities at diagnosis were arterial hypertension (33%), type 2 diabetes (29%) and obesity (24%).
conclusionsBased on previous Swedish studies, our results indicate that the incidence of cirrhosis in Sweden might be considerably higher than previously reported. It is uncertain if the incidence of cirrhosis has previously been underestimated or if an actual increment has occurred during the course of the most recent decade. The increased incidence rates of cirrhosis reported in Halland are multifactorial and most likely related to higher incidence rates among the elderly. Pre-obesity and obesity are common in cirrhosis and non-alcoholic fatty liver disease has become an important cause of cirrhosis in Halland.
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